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Anti-FOXC1 monoclonal antibody
Pre-made anti-FOXC1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FOXC1/FOXC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T99829-Ab-1/ GM-Tg-hg-T99829-Ab-2 | Anti-Human FOXC1 monoclonal antibody | Human |
| GM-Tg-rg-T99829-Ab-1/ GM-Tg-rg-T99829-Ab-2 | Anti-Rat FOXC1 monoclonal antibody | Rat |
| GM-Tg-mg-T99829-Ab-1/ GM-Tg-mg-T99829-Ab-2 | Anti-Mouse FOXC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T99829-Ab-1/ GM-Tg-cynog-T99829-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FOXC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T99829-Ab-1/ GM-Tg-felg-T99829-Ab-2 | Anti-Feline FOXC1 monoclonal antibody | Feline |
| GM-Tg-cang-T99829-Ab-1/ GM-Tg-cang-T99829-Ab-2 | Anti-Canine FOXC1 monoclonal antibody | Canine |
| GM-Tg-bovg-T99829-Ab-1/ GM-Tg-bovg-T99829-Ab-2 | Anti-Bovine FOXC1 monoclonal antibody | Bovine |
| GM-Tg-equg-T99829-Ab-1/ GM-Tg-equg-T99829-Ab-2 | Anti-Equine FOXC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T99829-Ab-1/ GM-Tg-hg-T99829-Ab-2; GM-Tg-rg-T99829-Ab-1/ GM-Tg-rg-T99829-Ab-2; GM-Tg-mg-T99829-Ab-1/ GM-Tg-mg-T99829-Ab-2; GM-Tg-cynog-T99829-Ab-1/ GM-Tg-cynog-T99829-Ab-2; GM-Tg-felg-T99829-Ab-1/ GM-Tg-felg-T99829-Ab-2; GM-Tg-cang-T99829-Ab-1/ GM-Tg-cang-T99829-Ab-2; GM-Tg-bovg-T99829-Ab-1/ GM-Tg-bovg-T99829-Ab-2; GM-Tg-equg-T99829-Ab-1/ GM-Tg-equg-T99829-Ab-2 |
| Products Name | Anti-FOXC1 monoclonal antibody |
| Format | mab |
| Target Name | FOXC1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FOXC1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T99829-Ag-1 | Recombinant multi-species FOXC1/ ARA/ ASGD3 protein |
| ORF Viral Vector | vGMAD000124 | human FOXC1 Adenovirus particle |
| ORF Viral Vector | pGMAD000124 | human FOXC1 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000326 | human FOXC1 Lentivirus particle |
| ORF Viral Vector | pGMLV000326 | human FOXC1 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000213 | mouse Foxc1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000213 | mouse Foxc1 Adenovirus particle |
Target information
| Target ID | GM-T99829 |
| Target Name | FOXC1 |
| Gene ID | 2296,17300,364706,722918,119867598,101088928,112443733,111769235 |
| Gene Symbol and Synonyms | ARA,ASGD3,ch,fkh-1,Fkh1,FKHL7,FOXC1,FREAC-3,FREAC3,frkhda,IGDA,IHG1,IRID1,Mf1,Mf4,RIEG3 |
| Uniprot Accession | Q12948 |
| Uniprot Entry Name | FOXC1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000054598 |
| Target Classification | N/A |
The target: FOXC1, gene name: FOXC1, also named as ARA, ASGD3, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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