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Anti-FKBP5 monoclonal antibody
Pre-made anti-FKBP5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FKBP5/FKBP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T98337-Ab-1/ GM-Tg-hg-T98337-Ab-2 | Anti-Human FKBP5 monoclonal antibody | Human |
| GM-Tg-rg-T98337-Ab-1/ GM-Tg-rg-T98337-Ab-2 | Anti-Rat FKBP5 monoclonal antibody | Rat |
| GM-Tg-mg-T98337-Ab-1/ GM-Tg-mg-T98337-Ab-2 | Anti-Mouse FKBP5 monoclonal antibody | Mouse |
| GM-Tg-cynog-T98337-Ab-1/ GM-Tg-cynog-T98337-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FKBP5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T98337-Ab-1/ GM-Tg-felg-T98337-Ab-2 | Anti-Feline FKBP5 monoclonal antibody | Feline |
| GM-Tg-cang-T98337-Ab-1/ GM-Tg-cang-T98337-Ab-2 | Anti-Canine FKBP5 monoclonal antibody | Canine |
| GM-Tg-bovg-T98337-Ab-1/ GM-Tg-bovg-T98337-Ab-2 | Anti-Bovine FKBP5 monoclonal antibody | Bovine |
| GM-Tg-equg-T98337-Ab-1/ GM-Tg-equg-T98337-Ab-2 | Anti-Equine FKBP5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T98337-Ab-1/ GM-Tg-hg-T98337-Ab-2; GM-Tg-rg-T98337-Ab-1/ GM-Tg-rg-T98337-Ab-2; GM-Tg-mg-T98337-Ab-1/ GM-Tg-mg-T98337-Ab-2; GM-Tg-cynog-T98337-Ab-1/ GM-Tg-cynog-T98337-Ab-2; GM-Tg-felg-T98337-Ab-1/ GM-Tg-felg-T98337-Ab-2; GM-Tg-cang-T98337-Ab-1/ GM-Tg-cang-T98337-Ab-2; GM-Tg-bovg-T98337-Ab-1/ GM-Tg-bovg-T98337-Ab-2; GM-Tg-equg-T98337-Ab-1/ GM-Tg-equg-T98337-Ab-2 |
| Products Name | Anti-FKBP5 monoclonal antibody |
| Format | mab |
| Target Name | FKBP5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FKBP5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T98337-Ag-1 | Recombinant multi-species FKBP5/ AIG61/ FKBP54 protein |
| ORF Viral Vector | pGMLV000378 | human FKBP5 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000378 | human FKBP5 Lentivirus particle |
| ORF Viral Vector | pGMAD000230 | mouse Fkbp5 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000230 | mouse Fkbp5 Adenovirus particle |
Target information
| Target ID | GM-T98337 |
| Target Name | FKBP5 |
| Gene ID | 2289,14229,361810,718957,481759,101099715,535704,100053546 |
| Gene Symbol and Synonyms | AIG6,D17Ertd592e,Dit1,FKBP-5,FKBP5,FKBP51,FKBP54,P54,PPIase,Ptg-10 |
| Uniprot Accession | Q13451 |
| Uniprot Entry Name | FKBP5_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000096060 |
| Target Classification | N/A |
The target: FKBP5, gene name: FKBP5, also named as AIG61, FKBP54, P54, PPIase, Ptg-10, FKBP5. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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