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Anti-AURKC monoclonal antibody
Pre-made anti-AURKC monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to AURKC/AURKC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T97592-Ab-1/ GM-Tg-hg-T97592-Ab-2 | Anti-Human AURKC monoclonal antibody | Human |
| GM-Tg-rg-T97592-Ab-1/ GM-Tg-rg-T97592-Ab-2 | Anti-Rat AURKC monoclonal antibody | Rat |
| GM-Tg-mg-T97592-Ab-1/ GM-Tg-mg-T97592-Ab-2 | Anti-Mouse AURKC monoclonal antibody | Mouse |
| GM-Tg-cynog-T97592-Ab-1/ GM-Tg-cynog-T97592-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AURKC monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T97592-Ab-1/ GM-Tg-felg-T97592-Ab-2 | Anti-Feline AURKC monoclonal antibody | Feline |
| GM-Tg-cang-T97592-Ab-1/ GM-Tg-cang-T97592-Ab-2 | Anti-Canine AURKC monoclonal antibody | Canine |
| GM-Tg-bovg-T97592-Ab-1/ GM-Tg-bovg-T97592-Ab-2 | Anti-Bovine AURKC monoclonal antibody | Bovine |
| GM-Tg-equg-T97592-Ab-1/ GM-Tg-equg-T97592-Ab-2 | Anti-Equine AURKC monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T97592-Ab-1/ GM-Tg-hg-T97592-Ab-2; GM-Tg-rg-T97592-Ab-1/ GM-Tg-rg-T97592-Ab-2; GM-Tg-mg-T97592-Ab-1/ GM-Tg-mg-T97592-Ab-2; GM-Tg-cynog-T97592-Ab-1/ GM-Tg-cynog-T97592-Ab-2; GM-Tg-felg-T97592-Ab-1/ GM-Tg-felg-T97592-Ab-2; GM-Tg-cang-T97592-Ab-1/ GM-Tg-cang-T97592-Ab-2; GM-Tg-bovg-T97592-Ab-1/ GM-Tg-bovg-T97592-Ab-2; GM-Tg-equg-T97592-Ab-1/ GM-Tg-equg-T97592-Ab-2 |
| Products Name | Anti-AURKC monoclonal antibody |
| Format | mab |
| Target Name | AURKC |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-AURKC monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T97592-Ag-1 | Recombinant multi-species AURKC/ AIE2/ AIK3 protein |
| ORF Viral Vector | pGMLP000985 | human AURKC Lentivirus plasmid |
| ORF Viral Vector | vGMLP000985 | human AURKC Lentivirus particle |
| ORF Viral Vector | pGMLPm004541 | mouse Aurkc Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004541 | mouse Aurkc Lentivirus particle |
Target information
| Target ID | GM-T97592 |
| Target Name | AURKC |
| Gene ID | 6795,20871,292554,709801,119870878,102899963,618599,100051177 |
| Gene Symbol and Synonyms | AIE1,AIE2,AIK3,ARK-3,ARK3,AurC,AURKC,aurora-C,HEL-S-90,IAK3,SPGF5,STK13 |
| Uniprot Accession | Q9UQB9 |
| Uniprot Entry Name | AURKC_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000105146 |
| Target Classification | Kinase |
The target: AURKC, gene name: AURKC, also named as AIE2, AIK3, ARK3, AurC, HEL-S-90, SPGF5, STK13, aurora-C. This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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