Anti-TICN1/ SPOCK1/ SPOCK functional antibody
Anti-TICN1/ SPOCK1/ SPOCK functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T96859-Ab-1/ GM-Tg-hg-T96859-Ab-2 | Anti-Human SPOCK1 monoclonal antibody | Human |
GM-Tg-rg-T96859-Ab-1/ GM-Tg-rg-T96859-Ab-2 | Anti-Rat SPOCK1 monoclonal antibody | Rat |
GM-Tg-mg-T96859-Ab-1/ GM-Tg-mg-T96859-Ab-2 | Anti-Mouse SPOCK1 monoclonal antibody | Mouse |
GM-Tg-cynog-T96859-Ab-1/ GM-Tg-cynog-T96859-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SPOCK1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T96859-Ab-1/ GM-Tg-felg-T96859-Ab-2 | Anti-Feline SPOCK1 monoclonal antibody | Feline |
GM-Tg-cang-T96859-Ab-1/ GM-Tg-cang-T96859-Ab-2 | Anti-Canine SPOCK1 monoclonal antibody | Canine |
GM-Tg-bovg-T96859-Ab-1/ GM-Tg-bovg-T96859-Ab-2 | Anti-Bovine SPOCK1 monoclonal antibody | Bovine |
GM-Tg-equg-T96859-Ab-1/ GM-Tg-equg-T96859-Ab-2 | Anti-Equine SPOCK1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T96859-Ab-1/ GM-Tg-hg-T96859-Ab-2; GM-Tg-rg-T96859-Ab-1/ GM-Tg-rg-T96859-Ab-2; GM-Tg-mg-T96859-Ab-1/ GM-Tg-mg-T96859-Ab-2; GM-Tg-cynog-T96859-Ab-1/ GM-Tg-cynog-T96859-Ab-2; GM-Tg-felg-T96859-Ab-1/ GM-Tg-felg-T96859-Ab-2; GM-Tg-cang-T96859-Ab-1/ GM-Tg-cang-T96859-Ab-2; GM-Tg-bovg-T96859-Ab-1/ GM-Tg-bovg-T96859-Ab-2; GM-Tg-equg-T96859-Ab-1/ GM-Tg-equg-T96859-Ab-2 |
Products Name | Anti-SPOCK1 monoclonal antibody |
Format | mab |
Target Name | SPOCK1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SPOCK1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T96859-Ag-1 | Recombinant multi-species TICN1/ SPOCK1/ SPOCK protein |
ORF Viral Vector | vGMAP000348 | Human SPOCK1 Adenovirus particle |
ORF Viral Vector | pGMAP000348 | Human SPOCK1 Adenovirus plasmid |
ORF Viral Vector | pGMLPm003331 | mouse Spock1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm003331 | mouse Spock1 Lentivirus particle |
Target information
Target ID | GM-T96859 |
Target Name | SPOCK1 |
Gene ID | 6695,20745,306759,715989,474688,101088716,511211,100072653 |
Gene Symbol and Synonyms | SPOCK,SPOCK1,TESTICAN,TIC1,Ticn1 |
Uniprot Accession | Q08629 |
Uniprot Entry Name | TICN1_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000152377 |
Target Classification | N/A |
The target: SPOCK1, gene name: SPOCK1, also named as SPOCK, TESTICAN, TIC1. This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.