Anti-TICN1/ SPOCK1/ SPOCK functional antibody

Anti-TICN1/ SPOCK1/ SPOCK functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SPOCK1/SPOCK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T96859-Ab-1/ GM-Tg-hg-T96859-Ab-2Anti-Human SPOCK1 monoclonal antibodyHuman
GM-Tg-rg-T96859-Ab-1/ GM-Tg-rg-T96859-Ab-2Anti-Rat SPOCK1 monoclonal antibodyRat
GM-Tg-mg-T96859-Ab-1/ GM-Tg-mg-T96859-Ab-2Anti-Mouse SPOCK1 monoclonal antibodyMouse
GM-Tg-cynog-T96859-Ab-1/ GM-Tg-cynog-T96859-Ab-2Anti-Cynomolgus/ Rhesus macaque SPOCK1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T96859-Ab-1/ GM-Tg-felg-T96859-Ab-2Anti-Feline SPOCK1 monoclonal antibodyFeline
GM-Tg-cang-T96859-Ab-1/ GM-Tg-cang-T96859-Ab-2Anti-Canine SPOCK1 monoclonal antibodyCanine
GM-Tg-bovg-T96859-Ab-1/ GM-Tg-bovg-T96859-Ab-2Anti-Bovine SPOCK1 monoclonal antibodyBovine
GM-Tg-equg-T96859-Ab-1/ GM-Tg-equg-T96859-Ab-2Anti-Equine SPOCK1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T96859-Ab-1/ GM-Tg-hg-T96859-Ab-2; GM-Tg-rg-T96859-Ab-1/ GM-Tg-rg-T96859-Ab-2;
GM-Tg-mg-T96859-Ab-1/ GM-Tg-mg-T96859-Ab-2; GM-Tg-cynog-T96859-Ab-1/ GM-Tg-cynog-T96859-Ab-2;
GM-Tg-felg-T96859-Ab-1/ GM-Tg-felg-T96859-Ab-2; GM-Tg-cang-T96859-Ab-1/ GM-Tg-cang-T96859-Ab-2;
GM-Tg-bovg-T96859-Ab-1/ GM-Tg-bovg-T96859-Ab-2; GM-Tg-equg-T96859-Ab-1/ GM-Tg-equg-T96859-Ab-2
Products NameAnti-SPOCK1 monoclonal antibody
Formatmab
Target NameSPOCK1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SPOCK1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T96859-Ag-1Recombinant multi-species TICN1/ SPOCK1/ SPOCK protein
    ORF Viral VectorvGMAP000348Human SPOCK1 Adenovirus particle
    ORF Viral VectorpGMAP000348Human SPOCK1 Adenovirus plasmid
    ORF Viral VectorpGMLPm003331mouse Spock1 Lentivirus plasmid
    ORF Viral VectorvGMLPm003331mouse Spock1 Lentivirus particle


    Target information

    Target IDGM-T96859
    Target NameSPOCK1
    Gene ID6695,20745,306759,715989,474688,101088716,511211,100072653
    Gene Symbol and SynonymsSPOCK,SPOCK1,TESTICAN,TIC1,Ticn1
    Uniprot AccessionQ08629
    Uniprot Entry NameTICN1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000152377
    Target ClassificationN/A

    The target: SPOCK1, gene name: SPOCK1, also named as SPOCK, TESTICAN, TIC1. This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.