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Anti-IL20/ IL-20/ IL10D functional antibody
Anti-IL20/ IL-20/ IL10D functional antibody for cell culture, ELISA & in-vivo assay
Go to IL20/IL20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T94482-Ab-1/ GM-Tg-hg-T94482-Ab-2 | Anti-Human IL20 monoclonal antibody | Human |
| GM-Tg-rg-T94482-Ab-1/ GM-Tg-rg-T94482-Ab-2 | Anti-Rat IL20 monoclonal antibody | Rat |
| GM-Tg-mg-T94482-Ab-1/ GM-Tg-mg-T94482-Ab-2 | Anti-Mouse IL20 monoclonal antibody | Mouse |
| GM-Tg-cynog-T94482-Ab-1/ GM-Tg-cynog-T94482-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL20 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T94482-Ab-1/ GM-Tg-felg-T94482-Ab-2 | Anti-Feline IL20 monoclonal antibody | Feline |
| GM-Tg-cang-T94482-Ab-1/ GM-Tg-cang-T94482-Ab-2 | Anti-Canine IL20 monoclonal antibody | Canine |
| GM-Tg-bovg-T94482-Ab-1/ GM-Tg-bovg-T94482-Ab-2 | Anti-Bovine IL20 monoclonal antibody | Bovine |
| GM-Tg-equg-T94482-Ab-1/ GM-Tg-equg-T94482-Ab-2 | Anti-Equine IL20 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T94482-Ab-1/ GM-Tg-hg-T94482-Ab-2; GM-Tg-rg-T94482-Ab-1/ GM-Tg-rg-T94482-Ab-2; GM-Tg-mg-T94482-Ab-1/ GM-Tg-mg-T94482-Ab-2; GM-Tg-cynog-T94482-Ab-1/ GM-Tg-cynog-T94482-Ab-2; GM-Tg-felg-T94482-Ab-1/ GM-Tg-felg-T94482-Ab-2; GM-Tg-cang-T94482-Ab-1/ GM-Tg-cang-T94482-Ab-2; GM-Tg-bovg-T94482-Ab-1/ GM-Tg-bovg-T94482-Ab-2; GM-Tg-equg-T94482-Ab-1/ GM-Tg-equg-T94482-Ab-2 |
| Products Name | Anti-IL20 monoclonal antibody |
| Format | mab |
| Target Name | IL20 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-217 | Pre-Made Fletikumab biosimilar, Whole mAb, Anti-IL20 Antibody: Anti-IL-20/IL10D/ZCYTO10 therapeutic antibody |
| Target Antigen | GM-Tg-g-T94482-Ag-1 | Recombinant multi-species IL20/ IL-20/ IL10D protein |
| Cytokine | GM-Tg-g-T94482-Ag-1 | Interleukin 20 (IL20) protein |
Target information
| Target ID | GM-T94482 |
| Target Name | IL20 |
| Gene ID | 50604,58181,681112,694689,609203,101096130,515533,100055632 |
| Gene Symbol and Synonyms | If2d,IL-20,IL10D,IL20,ZCYTO10 |
| Uniprot Accession | Q9NYY1 |
| Uniprot Entry Name | IL20_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000162891 |
| Target Classification | N/A |
The target: IL20, gene name: IL20, also named as IL-20, IL10D, ZCYTO10. The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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