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Anti-PACR/ PAC1R/ ADCYAP1R1 monoclonal antibody
Anti-PACR/ PAC1R/ ADCYAP1R1 antibody for FACS & in-vivo assay
Go to PAC1R/ADCYAP1R1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T92185-Ab-1/ GM-Tg-hg-T92185-Ab-2 | Anti-Human PAC1R/ADCYAP1R1 monoclonal antibody | Human |
| GM-Tg-rg-T92185-Ab-1/ GM-Tg-rg-T92185-Ab-2 | Anti-Rat PAC1R/ADCYAP1R1 monoclonal antibody | Rat |
| GM-Tg-mg-T92185-Ab-1/ GM-Tg-mg-T92185-Ab-2 | Anti-Mouse PAC1R/ADCYAP1R1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T92185-Ab-1/ GM-Tg-cynog-T92185-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PAC1R/ADCYAP1R1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T92185-Ab-1/ GM-Tg-felg-T92185-Ab-2 | Anti-Feline PAC1R/ADCYAP1R1 monoclonal antibody | Feline |
| GM-Tg-cang-T92185-Ab-1/ GM-Tg-cang-T92185-Ab-2 | Anti-Canine PAC1R/ADCYAP1R1 monoclonal antibody | Canine |
| GM-Tg-bovg-T92185-Ab-1/ GM-Tg-bovg-T92185-Ab-2 | Anti-Bovine PAC1R/ADCYAP1R1 monoclonal antibody | Bovine |
| GM-Tg-equg-T92185-Ab-1/ GM-Tg-equg-T92185-Ab-2 | Anti-Equine PAC1R/ADCYAP1R1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T92185-Ab-1/ GM-Tg-hg-T92185-Ab-2; GM-Tg-rg-T92185-Ab-1/ GM-Tg-rg-T92185-Ab-2; GM-Tg-mg-T92185-Ab-1/ GM-Tg-mg-T92185-Ab-2; GM-Tg-cynog-T92185-Ab-1/ GM-Tg-cynog-T92185-Ab-2; GM-Tg-felg-T92185-Ab-1/ GM-Tg-felg-T92185-Ab-2; GM-Tg-cang-T92185-Ab-1/ GM-Tg-cang-T92185-Ab-2; GM-Tg-bovg-T92185-Ab-1/ GM-Tg-bovg-T92185-Ab-2; GM-Tg-equg-T92185-Ab-1/ GM-Tg-equg-T92185-Ab-2 |
| Products Name | Anti-PAC1R/ADCYAP1R1 monoclonal antibody |
| Format | mab |
| Target Name | PAC1R |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PAC1R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-643 | Pre-Made Zelminemab biosimilar, Whole mAb, Anti-ADCYAP1R1/PAC1R Antibody: Anti-PAC1/PACAPR/PACAPRI therapeutic antibody |
| Target Antigen | Products Developing | Multi-species PACR/ PAC1R/ ADCYAP1R1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm002115 | mouse Adcyap1r1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002116 | mouse Adcyap1r1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002115 | mouse Adcyap1r1 Lentivirus particle |
| ORF Viral Vector | vGMLPm002116 | mouse Adcyap1r1 Lentivirus particle |
Target information
| Target ID | GM-T92185 |
| Target Name | PAC1R |
| Gene ID | 117,11517,24167,695483,482386,101088396,319095,100069948 |
| Gene Symbol and Synonyms | 2900024I10Rik,ADCYAP1R1,PAC1,PAC1-R,PAC1R,PACAP-R1,PACAP-R1A,PACAP1-R,PACAPR,PACAPR1,PACAPR1A,PACAPRI |
| Uniprot Accession | P41586,P32215,Q29627 |
| Uniprot Entry Name | PACR_HUMAN,PACR_RAT,PACR_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | N/A |
| Gene Ensembl | ENSG00000078549 |
| Target Classification | GPCR |
The target: PAC1R, gene name: ADCYAP1R1, also named as PAC1, PAC1R, PACAPR, PACAPRI. This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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