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Anti-CREB1 monoclonal antibody
Pre-made anti-CREB1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CREB1/CREB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T92098-Ab-1/ GM-Tg-hg-T92098-Ab-2 | Anti-Human CREB1 monoclonal antibody | Human |
| GM-Tg-rg-T92098-Ab-1/ GM-Tg-rg-T92098-Ab-2 | Anti-Rat CREB1 monoclonal antibody | Rat |
| GM-Tg-mg-T92098-Ab-1/ GM-Tg-mg-T92098-Ab-2 | Anti-Mouse CREB1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T92098-Ab-1/ GM-Tg-cynog-T92098-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CREB1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T92098-Ab-1/ GM-Tg-felg-T92098-Ab-2 | Anti-Feline CREB1 monoclonal antibody | Feline |
| GM-Tg-cang-T92098-Ab-1/ GM-Tg-cang-T92098-Ab-2 | Anti-Canine CREB1 monoclonal antibody | Canine |
| GM-Tg-bovg-T92098-Ab-1/ GM-Tg-bovg-T92098-Ab-2 | Anti-Bovine CREB1 monoclonal antibody | Bovine |
| GM-Tg-equg-T92098-Ab-1/ GM-Tg-equg-T92098-Ab-2 | Anti-Equine CREB1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T92098-Ab-1/ GM-Tg-hg-T92098-Ab-2; GM-Tg-rg-T92098-Ab-1/ GM-Tg-rg-T92098-Ab-2; GM-Tg-mg-T92098-Ab-1/ GM-Tg-mg-T92098-Ab-2; GM-Tg-cynog-T92098-Ab-1/ GM-Tg-cynog-T92098-Ab-2; GM-Tg-felg-T92098-Ab-1/ GM-Tg-felg-T92098-Ab-2; GM-Tg-cang-T92098-Ab-1/ GM-Tg-cang-T92098-Ab-2; GM-Tg-bovg-T92098-Ab-1/ GM-Tg-bovg-T92098-Ab-2; GM-Tg-equg-T92098-Ab-1/ GM-Tg-equg-T92098-Ab-2 |
| Products Name | Anti-CREB1 monoclonal antibody |
| Format | mab |
| Target Name | CREB1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CREB1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T92098-Ag-1 | Recombinant multi-species CREB1/ CREB/ CREB-1 protein |
| ORF Viral Vector | pGMLP002666 | human CREB1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002666 | human CREB1 Lentivirus particle |
| ORF Viral Vector | pGMLV000036 | rat Creb1 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000181 | house mouse Creb1 AAV plasmid |
| ORF Viral Vector | vGMLV000036 | rat Creb1 Lentivirus particle |
| ORF Viral Vector | vGMAAV000181 | house mouse Creb1 AAV particle |
Target information
| Target ID | GM-T92098 |
| Target Name | CREB1 |
| Gene ID | 1385,12912,81646,708717,607922,101091299,281713,100066388 |
| Gene Symbol and Synonyms | 2310001E10Rik,3526402H21Rik,CREB,CREB-1,CREB1 |
| Uniprot Accession | P16220,P15337,P27925 |
| Uniprot Entry Name | CREB1_HUMAN,CREB1_RAT,CREB1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000118260 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CREB1, gene name: CREB1, also named as CREB, CREB-1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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