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Anti-PDGFD/ IEGF/ MSTP036 functional antibody
Anti-PDGFD/ IEGF/ MSTP036 functional antibody for cell culture, ELISA & in-vivo assay
Go to PDGFD/PDGFD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T90464-Ab-1/ GM-Tg-hg-T90464-Ab-2 | Anti-Human PDGFD monoclonal antibody | Human |
| GM-Tg-rg-T90464-Ab-1/ GM-Tg-rg-T90464-Ab-2 | Anti-Rat PDGFD monoclonal antibody | Rat |
| GM-Tg-mg-T90464-Ab-1/ GM-Tg-mg-T90464-Ab-2 | Anti-Mouse PDGFD monoclonal antibody | Mouse |
| GM-Tg-cynog-T90464-Ab-1/ GM-Tg-cynog-T90464-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PDGFD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T90464-Ab-1/ GM-Tg-felg-T90464-Ab-2 | Anti-Feline PDGFD monoclonal antibody | Feline |
| GM-Tg-cang-T90464-Ab-1/ GM-Tg-cang-T90464-Ab-2 | Anti-Canine PDGFD monoclonal antibody | Canine |
| GM-Tg-bovg-T90464-Ab-1/ GM-Tg-bovg-T90464-Ab-2 | Anti-Bovine PDGFD monoclonal antibody | Bovine |
| GM-Tg-equg-T90464-Ab-1/ GM-Tg-equg-T90464-Ab-2 | Anti-Equine PDGFD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T90464-Ab-1/ GM-Tg-hg-T90464-Ab-2; GM-Tg-rg-T90464-Ab-1/ GM-Tg-rg-T90464-Ab-2; GM-Tg-mg-T90464-Ab-1/ GM-Tg-mg-T90464-Ab-2; GM-Tg-cynog-T90464-Ab-1/ GM-Tg-cynog-T90464-Ab-2; GM-Tg-felg-T90464-Ab-1/ GM-Tg-felg-T90464-Ab-2; GM-Tg-cang-T90464-Ab-1/ GM-Tg-cang-T90464-Ab-2; GM-Tg-bovg-T90464-Ab-1/ GM-Tg-bovg-T90464-Ab-2; GM-Tg-equg-T90464-Ab-1/ GM-Tg-equg-T90464-Ab-2 |
| Products Name | Anti-PDGFD monoclonal antibody |
| Format | mab |
| Target Name | PDGFD |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PDGFD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T90464-Ag-1 | Recombinant multi-species PDGFD/ IEGF/ MSTP036 protein |
| Cytokine | GM-Tg-g-T90464-Ag-1 | platelet derived growth factor D (PDGFD) protein |
| ORF Viral Vector | pGMLP002789 | human PDGFD Lentivirus plasmid |
| ORF Viral Vector | vGMLP002789 | human PDGFD Lentivirus particle |
| ORF Viral Vector | pGMLPm001091 | mouse Pdgfd Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001091 | mouse Pdgfd Lentivirus particle |
Target information
| Target ID | GM-T90464 |
| Target Name | PDGFD |
| Gene ID | 80310,71785,66018,704310,479460,101084984,525931,100061488 |
| Gene Symbol and Synonyms | 1110003I09Rik,IEGF,MSTP036,PDGFD,rSCDGF-B,SCDGF-B,SCDGFB |
| Uniprot Accession | Q9GZP0,Q9EQT1 |
| Uniprot Entry Name | PDGFD_HUMAN,PDGFD_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000170962 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: PDGFD, gene name: PDGFD, also named as IEGF, MSTP036, SCDGF-B, SCDGFB. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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