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Anti-MAP3K10 monoclonal antibody
Pre-made anti-MAP3K10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MAP3K10/MAP3K10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T89323-Ab-1/ GM-Tg-hg-T89323-Ab-2 | Anti-Human MAP3K10 monoclonal antibody | Human |
| GM-Tg-rg-T89323-Ab-1/ GM-Tg-rg-T89323-Ab-2 | Anti-Rat MAP3K10 monoclonal antibody | Rat |
| GM-Tg-mg-T89323-Ab-1/ GM-Tg-mg-T89323-Ab-2 | Anti-Mouse MAP3K10 monoclonal antibody | Mouse |
| GM-Tg-cynog-T89323-Ab-1/ GM-Tg-cynog-T89323-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MAP3K10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T89323-Ab-1/ GM-Tg-felg-T89323-Ab-2 | Anti-Feline MAP3K10 monoclonal antibody | Feline |
| GM-Tg-cang-T89323-Ab-1/ GM-Tg-cang-T89323-Ab-2 | Anti-Canine MAP3K10 monoclonal antibody | Canine |
| GM-Tg-bovg-T89323-Ab-1/ GM-Tg-bovg-T89323-Ab-2 | Anti-Bovine MAP3K10 monoclonal antibody | Bovine |
| GM-Tg-equg-T89323-Ab-1/ GM-Tg-equg-T89323-Ab-2 | Anti-Equine MAP3K10 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T89323-Ab-1/ GM-Tg-hg-T89323-Ab-2; GM-Tg-rg-T89323-Ab-1/ GM-Tg-rg-T89323-Ab-2; GM-Tg-mg-T89323-Ab-1/ GM-Tg-mg-T89323-Ab-2; GM-Tg-cynog-T89323-Ab-1/ GM-Tg-cynog-T89323-Ab-2; GM-Tg-felg-T89323-Ab-1/ GM-Tg-felg-T89323-Ab-2; GM-Tg-cang-T89323-Ab-1/ GM-Tg-cang-T89323-Ab-2; GM-Tg-bovg-T89323-Ab-1/ GM-Tg-bovg-T89323-Ab-2; GM-Tg-equg-T89323-Ab-1/ GM-Tg-equg-T89323-Ab-2 |
| Products Name | Anti-MAP3K10 monoclonal antibody |
| Format | mab |
| Target Name | MAP3K10 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MAP3K10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T89323-Ag-1 | Recombinant multi-species M3K10/ MAP3K10/ MEKK10 protein |
| ORF Viral Vector | vGMLV000289 | human MAP3K10 Lentivirus particle |
| ORF Viral Vector | pGMLV000289 | human MAP3K10 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000499 | human MAP3K10 Lentivirus particle |
| ORF Viral Vector | pGMLV000499 | human MAP3K10 Lentivirus plasmid |
Target information
| Target ID | GM-T89323 |
| Target Name | MAP3K10 |
| Gene ID | 4294,269881,308463,700477,484504,101089731,781037,100067981 |
| Gene Symbol and Synonyms | MAP3K10,MEKK10,MLK2,MST |
| Uniprot Accession | Q02779,D3ZG83 |
| Uniprot Entry Name | M3K10_HUMAN,M3K10_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000130758 |
| Target Classification | Kinase |
The target: MAP3K10, gene name: MAP3K10, also named as MEKK10, MLK2, MST. The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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