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Anti-RAC1 monoclonal antibody
Pre-made anti-RAC1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RAC1/RAC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T88752-Ab-1/ GM-Tg-hg-T88752-Ab-2 | Anti-Human RAC1 monoclonal antibody | Human |
| GM-Tg-rg-T88752-Ab-1/ GM-Tg-rg-T88752-Ab-2 | Anti-Rat RAC1 monoclonal antibody | Rat |
| GM-Tg-mg-T88752-Ab-1/ GM-Tg-mg-T88752-Ab-2 | Anti-Mouse RAC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T88752-Ab-1/ GM-Tg-cynog-T88752-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RAC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T88752-Ab-1/ GM-Tg-felg-T88752-Ab-2 | Anti-Feline RAC1 monoclonal antibody | Feline |
| GM-Tg-cang-T88752-Ab-1/ GM-Tg-cang-T88752-Ab-2 | Anti-Canine RAC1 monoclonal antibody | Canine |
| GM-Tg-bovg-T88752-Ab-1/ GM-Tg-bovg-T88752-Ab-2 | Anti-Bovine RAC1 monoclonal antibody | Bovine |
| GM-Tg-equg-T88752-Ab-1/ GM-Tg-equg-T88752-Ab-2 | Anti-Equine RAC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T88752-Ab-1/ GM-Tg-hg-T88752-Ab-2; GM-Tg-rg-T88752-Ab-1/ GM-Tg-rg-T88752-Ab-2; GM-Tg-mg-T88752-Ab-1/ GM-Tg-mg-T88752-Ab-2; GM-Tg-cynog-T88752-Ab-1/ GM-Tg-cynog-T88752-Ab-2; GM-Tg-felg-T88752-Ab-1/ GM-Tg-felg-T88752-Ab-2; GM-Tg-cang-T88752-Ab-1/ GM-Tg-cang-T88752-Ab-2; GM-Tg-bovg-T88752-Ab-1/ GM-Tg-bovg-T88752-Ab-2; GM-Tg-equg-T88752-Ab-1/ GM-Tg-equg-T88752-Ab-2 |
| Products Name | Anti-RAC1 monoclonal antibody |
| Format | mab |
| Target Name | RAC1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RAC1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T88752-Ag-1 | Recombinant multi-species RAC1/ MIG5/ MRD48 protein |
| ORF Viral Vector | pGMAP000586 | Human RAC1 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000095 | human RAC1 Lentivirus particle |
| ORF Viral Vector | vGMAP000586 | Human RAC1 Adenovirus particle |
| ORF Viral Vector | pGMLV000177 | human RAC1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000095 | human RAC1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000178 | human RAC1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000177 | human RAC1 Lentivirus particle |
| ORF Viral Vector | vGMLV000178 | human RAC1 Lentivirus particle |
| ORF Viral Vector | pGMLPm000606 | mouse Rac1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000606 | mouse Rac1 Lentivirus particle |
Target information
| Target ID | GM-T88752 |
| Target Name | RAC1 |
| Gene ID | 5879,19353,363875,717755,403955,101101277,281440,100061732 |
| Gene Symbol and Synonyms | D5Ertd559e,MIG5,MRD48,p21-Rac1,Rac-1,RAC1,RAC2,TC-25 |
| Uniprot Accession | P63000,Q6RUV5,P62999,P62998 |
| Uniprot Entry Name | RAC1_HUMAN,RAC1_RAT,RAC1_CANLF,RAC1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000136238 |
| Target Classification | N/A |
The target: RAC1, gene name: RAC1, also named as MIG5, MRD48, Rac-1, TC-25, p21-Rac1. The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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