Anti-FOXM1 monoclonal antibody

Pre-made anti-FOXM1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FOXM1/FOXM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T85273-Ab-1/ GM-Tg-hg-T85273-Ab-2Anti-Human FOXM1 monoclonal antibodyHuman
GM-Tg-rg-T85273-Ab-1/ GM-Tg-rg-T85273-Ab-2Anti-Rat FOXM1 monoclonal antibodyRat
GM-Tg-mg-T85273-Ab-1/ GM-Tg-mg-T85273-Ab-2Anti-Mouse FOXM1 monoclonal antibodyMouse
GM-Tg-cynog-T85273-Ab-1/ GM-Tg-cynog-T85273-Ab-2Anti-Cynomolgus/ Rhesus macaque FOXM1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T85273-Ab-1/ GM-Tg-felg-T85273-Ab-2Anti-Feline FOXM1 monoclonal antibodyFeline
GM-Tg-cang-T85273-Ab-1/ GM-Tg-cang-T85273-Ab-2Anti-Canine FOXM1 monoclonal antibodyCanine
GM-Tg-bovg-T85273-Ab-1/ GM-Tg-bovg-T85273-Ab-2Anti-Bovine FOXM1 monoclonal antibodyBovine
GM-Tg-equg-T85273-Ab-1/ GM-Tg-equg-T85273-Ab-2Anti-Equine FOXM1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T85273-Ab-1/ GM-Tg-hg-T85273-Ab-2; GM-Tg-rg-T85273-Ab-1/ GM-Tg-rg-T85273-Ab-2;
GM-Tg-mg-T85273-Ab-1/ GM-Tg-mg-T85273-Ab-2; GM-Tg-cynog-T85273-Ab-1/ GM-Tg-cynog-T85273-Ab-2;
GM-Tg-felg-T85273-Ab-1/ GM-Tg-felg-T85273-Ab-2; GM-Tg-cang-T85273-Ab-1/ GM-Tg-cang-T85273-Ab-2;
GM-Tg-bovg-T85273-Ab-1/ GM-Tg-bovg-T85273-Ab-2; GM-Tg-equg-T85273-Ab-1/ GM-Tg-equg-T85273-Ab-2
Products NameAnti-FOXM1 monoclonal antibody
Formatmab
Target NameFOXM1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FOXM1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T85273-Ag-1Recombinant multi-species FOXM1/ FKHL16A/ FOXM1B protein
    ORF Viral VectorpGMLV000772human FOXM1 Lentivirus plasmid
    ORF Viral VectorvGMLV000772human FOXM1 Lentivirus particle
    ORF Viral VectorpGMAD000355rat Foxm1 Adenovirus plasmid
    ORF Viral VectorpGMAD000474Norway rat Foxm1 Adenovirus plasmid
    ORF Viral VectorpGMAD000606house mouse Foxm1 Adenovirus plasmid
    ORF Viral VectorpGMLPm003592mouse Foxm1 Lentivirus plasmid
    ORF Viral VectorvGMAD000355rat Foxm1 Adenovirus particle
    ORF Viral VectorvGMAD000474Norway rat Foxm1 Adenovirus particle
    ORF Viral VectorvGMAD000606house mouse Foxm1 Adenovirus particle
    ORF Viral VectorvGMLPm003592mouse Foxm1 Lentivirus particle


    Target information

    Target IDGM-T85273
    Target NameFOXM1
    Gene ID2305,14235,58921,708805,486743,101089113,513643,100050775
    Gene Symbol and SynonymsFkh16,FKHL16,FOXM1,FOXM1A,FOXM1B,FOXM1C,HFH-11,HFH-11B,HFH11,HNF-3,INS-1,MPHOSPH2,Mpm2,MPP-2,MPP2,PIG29,TRIDENT,WIN
    Uniprot AccessionQ08050,P97691
    Uniprot Entry NameFOXM1_HUMAN,FOXM1_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target, Immuno-oncology Target
    DiseaseCancer
    Gene EnsemblENSG00000111206
    Target ClassificationCheckpoint-Immuno Oncology, Tumor-associated antigen (TAA)

    The target: FOXM1, gene name: FOXM1, also named as FKHL16A, FOXM1B, FOXM1C, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TRIDENT, FOXM1. The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.