Anti-™SB4X monoclonal antibody
Pre-made anti-™SB4X monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T85005-Ab-1/ GM-Tg-hg-T85005-Ab-2 | Anti-Human ™SB4X monoclonal antibody | Human |
GM-Tg-rg-T85005-Ab-1/ GM-Tg-rg-T85005-Ab-2 | Anti-Rat ™SB4X monoclonal antibody | Rat |
GM-Tg-mg-T85005-Ab-1/ GM-Tg-mg-T85005-Ab-2 | Anti-Mouse ™SB4X monoclonal antibody | Mouse |
GM-Tg-cynog-T85005-Ab-1/ GM-Tg-cynog-T85005-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ™SB4X monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T85005-Ab-1/ GM-Tg-felg-T85005-Ab-2 | Anti-Feline ™SB4X monoclonal antibody | Feline |
GM-Tg-cang-T85005-Ab-1/ GM-Tg-cang-T85005-Ab-2 | Anti-Canine ™SB4X monoclonal antibody | Canine |
GM-Tg-bovg-T85005-Ab-1/ GM-Tg-bovg-T85005-Ab-2 | Anti-Bovine ™SB4X monoclonal antibody | Bovine |
GM-Tg-equg-T85005-Ab-1/ GM-Tg-equg-T85005-Ab-2 | Anti-Equine ™SB4X monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T85005-Ab-1/ GM-Tg-hg-T85005-Ab-2; GM-Tg-rg-T85005-Ab-1/ GM-Tg-rg-T85005-Ab-2; GM-Tg-mg-T85005-Ab-1/ GM-Tg-mg-T85005-Ab-2; GM-Tg-cynog-T85005-Ab-1/ GM-Tg-cynog-T85005-Ab-2; GM-Tg-felg-T85005-Ab-1/ GM-Tg-felg-T85005-Ab-2; GM-Tg-cang-T85005-Ab-1/ GM-Tg-cang-T85005-Ab-2; GM-Tg-bovg-T85005-Ab-1/ GM-Tg-bovg-T85005-Ab-2; GM-Tg-equg-T85005-Ab-1/ GM-Tg-equg-T85005-Ab-2 |
Products Name | Anti-™SB4X monoclonal antibody |
Format | mab |
Target Name | ™SB4X |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-™SB4X monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T85005-Ag-1 | Recombinant multi-species TYB4/ ™SB4X/ FX protein |
ORF Viral Vector | vGMLP003137 | human ™SB4X Lentivirus particle |
ORF Viral Vector | pGMLP003137 | human ™SB4X Lentivirus plasmid |
ORF Viral Vector | vGMLV000075 | human ™SB4X Lentivirus particle |
ORF Viral Vector | pGMLV000075 | human ™SB4X Lentivirus plasmid |
ORF Viral Vector | pGMLPm001871 | mouse Tmsb4x Lentivirus plasmid |
ORF Viral Vector | vGMLPm001871 | mouse Tmsb4x Lentivirus particle |
Target information
Target ID | GM-T85005 |
Target Name | ™SB4X |
Gene ID | 7114,19241,81814,710959,100684977,101088815,282386,100034015 |
Gene Symbol and Synonyms | FX,P™B4,Tb4,TB4X,Tbeta4,THYB4,™SB4,™SB4X |
Uniprot Accession | P62328,P62329,P62327 |
Uniprot Entry Name | TYB4_HUMAN,TYB4_RAT,TYB4_HORSE |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000205542 |
Target Classification | N/A |
The target: ™SB4X, gene name: ™SB4X, also named as FX, P™B4, TB4X, ™SB4. This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.