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Anti-MC3R/ BMIQ9/ MC3 monoclonal antibody
Anti-MC3R/ BMIQ9/ MC3 antibody for FACS & in-vivo assay
Go to MC3R/MC3R products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T76846-Ab-1/ GM-Tg-hg-T76846-Ab-2 | Anti-Human MC3R monoclonal antibody | Human |
| GM-Tg-rg-T76846-Ab-1/ GM-Tg-rg-T76846-Ab-2 | Anti-Rat MC3R monoclonal antibody | Rat |
| GM-Tg-mg-T76846-Ab-1/ GM-Tg-mg-T76846-Ab-2 | Anti-Mouse MC3R monoclonal antibody | Mouse |
| GM-Tg-cynog-T76846-Ab-1/ GM-Tg-cynog-T76846-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MC3R monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T76846-Ab-1/ GM-Tg-felg-T76846-Ab-2 | Anti-Feline MC3R monoclonal antibody | Feline |
| GM-Tg-cang-T76846-Ab-1/ GM-Tg-cang-T76846-Ab-2 | Anti-Canine MC3R monoclonal antibody | Canine |
| GM-Tg-bovg-T76846-Ab-1/ GM-Tg-bovg-T76846-Ab-2 | Anti-Bovine MC3R monoclonal antibody | Bovine |
| GM-Tg-equg-T76846-Ab-1/ GM-Tg-equg-T76846-Ab-2 | Anti-Equine MC3R monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T76846-Ab-1/ GM-Tg-hg-T76846-Ab-2; GM-Tg-rg-T76846-Ab-1/ GM-Tg-rg-T76846-Ab-2; GM-Tg-mg-T76846-Ab-1/ GM-Tg-mg-T76846-Ab-2; GM-Tg-cynog-T76846-Ab-1/ GM-Tg-cynog-T76846-Ab-2; GM-Tg-felg-T76846-Ab-1/ GM-Tg-felg-T76846-Ab-2; GM-Tg-cang-T76846-Ab-1/ GM-Tg-cang-T76846-Ab-2; GM-Tg-bovg-T76846-Ab-1/ GM-Tg-bovg-T76846-Ab-2; GM-Tg-equg-T76846-Ab-1/ GM-Tg-equg-T76846-Ab-2 |
| Products Name | Anti-MC3R monoclonal antibody |
| Format | mab |
| Target Name | MC3R |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MC3R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MC3R/ BMIQ9/ MC3 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP004498 | human MC3R Lentivirus plasmid |
| ORF Viral Vector | vGMLP004498 | human MC3R Lentivirus particle |
| ORF Viral Vector | pGMLPm000489 | mouse Mc3r Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000489 | mouse Mc3r Lentivirus particle |
Target information
| Target ID | GM-T76846 |
| Target Name | MC3R |
| Gene ID | 4159,17201,29310,698439,485938,101091434,505405,100054477 |
| Gene Symbol and Synonyms | BMIQ9,MC3,MC3-R,MC3R,OB20,OQTL |
| Uniprot Accession | P41968,P32244 |
| Uniprot Entry Name | MC3R_HUMAN,MC3R_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000124089 |
| Target Classification | GPCR |
The target: MC3R, gene name: MC3R, also named as BMIQ9, MC3, MC3-R, OB20, OQTL. This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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