Anti-CD36/ BDPLT10/ CHDS7 monoclonal antibody

Anti-CD36/ BDPLT10/ CHDS7 antibody for FACS & in-vivo assay

Target products collectionGo to CD36/CD36 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T76286-Ab-1/ GM-Tg-hg-T76286-Ab-2Anti-Human CD36 monoclonal antibodyHuman
GM-Tg-rg-T76286-Ab-1/ GM-Tg-rg-T76286-Ab-2Anti-Rat CD36 monoclonal antibodyRat
GM-Tg-mg-T76286-Ab-1/ GM-Tg-mg-T76286-Ab-2Anti-Mouse CD36 monoclonal antibodyMouse
GM-Tg-cynog-T76286-Ab-1/ GM-Tg-cynog-T76286-Ab-2Anti-Cynomolgus/ Rhesus macaque CD36 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T76286-Ab-1/ GM-Tg-felg-T76286-Ab-2Anti-Feline CD36 monoclonal antibodyFeline
GM-Tg-cang-T76286-Ab-1/ GM-Tg-cang-T76286-Ab-2Anti-Canine CD36 monoclonal antibodyCanine
GM-Tg-bovg-T76286-Ab-1/ GM-Tg-bovg-T76286-Ab-2Anti-Bovine CD36 monoclonal antibodyBovine
GM-Tg-equg-T76286-Ab-1/ GM-Tg-equg-T76286-Ab-2Anti-Equine CD36 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T76286-Ab-1/ GM-Tg-hg-T76286-Ab-2; GM-Tg-rg-T76286-Ab-1/ GM-Tg-rg-T76286-Ab-2;
GM-Tg-mg-T76286-Ab-1/ GM-Tg-mg-T76286-Ab-2; GM-Tg-cynog-T76286-Ab-1/ GM-Tg-cynog-T76286-Ab-2;
GM-Tg-felg-T76286-Ab-1/ GM-Tg-felg-T76286-Ab-2; GM-Tg-cang-T76286-Ab-1/ GM-Tg-cang-T76286-Ab-2;
GM-Tg-bovg-T76286-Ab-1/ GM-Tg-bovg-T76286-Ab-2; GM-Tg-equg-T76286-Ab-1/ GM-Tg-equg-T76286-Ab-2
Products NameAnti-CD36 monoclonal antibody
Formatmab
Target NameCD36
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CD36 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CD36/ BDPLT10/ CHDS7 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMAP000500Human CD36 Adenovirus particle
    ORF Viral VectorpGMLV000435human CD36 Lentivirus plasmid
    ORF Viral VectorvGMLV000435human CD36 Lentivirus particle
    ORF Viral VectorpGMAP000500Human CD36 Adenovirus plasmid
    ORF Viral VectorpGMAD000077mouse Cd36 Adenovirus plasmid
    ORF Viral VectorpGMAAV000035mouse Cd36 AAV plasmid
    ORF Viral VectorvGMAD000077mouse Cd36 Adenovirus particle
    ORF Viral VectorvGMAAV000035mouse Cd36 AAV particle


    Target information

    Target IDGM-T76286
    Target NameCD36
    Gene ID948,12491,574296,475931,101093842,281052,100049847
    Gene Symbol and SynonymsBDPLT10,CD36,CHDS7,FAT,GP3B,GP4,GPIIIB,GPIV,PAS-4,PASIV,SCARB3
    Uniprot AccessionP16671,P26201
    Uniprot Entry NameCD36_HUMAN,CD36_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseCancer
    Gene EnsemblENSG00000135218
    Target ClassificationTumor-associated antigen (TAA)

    The target: CD36, gene name: CD36, also named as BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3. The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.