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Anti-MYD88 monoclonal antibody
Pre-made anti-MYD88 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MYD88/MYD88 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T75476-Ab-1/ GM-Tg-hg-T75476-Ab-2 | Anti-Human MYD88 monoclonal antibody | Human |
| GM-Tg-rg-T75476-Ab-1/ GM-Tg-rg-T75476-Ab-2 | Anti-Rat MYD88 monoclonal antibody | Rat |
| GM-Tg-mg-T75476-Ab-1/ GM-Tg-mg-T75476-Ab-2 | Anti-Mouse MYD88 monoclonal antibody | Mouse |
| GM-Tg-cynog-T75476-Ab-1/ GM-Tg-cynog-T75476-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MYD88 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T75476-Ab-1/ GM-Tg-felg-T75476-Ab-2 | Anti-Feline MYD88 monoclonal antibody | Feline |
| GM-Tg-cang-T75476-Ab-1/ GM-Tg-cang-T75476-Ab-2 | Anti-Canine MYD88 monoclonal antibody | Canine |
| GM-Tg-bovg-T75476-Ab-1/ GM-Tg-bovg-T75476-Ab-2 | Anti-Bovine MYD88 monoclonal antibody | Bovine |
| GM-Tg-equg-T75476-Ab-1/ GM-Tg-equg-T75476-Ab-2 | Anti-Equine MYD88 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T75476-Ab-1/ GM-Tg-hg-T75476-Ab-2; GM-Tg-rg-T75476-Ab-1/ GM-Tg-rg-T75476-Ab-2; GM-Tg-mg-T75476-Ab-1/ GM-Tg-mg-T75476-Ab-2; GM-Tg-cynog-T75476-Ab-1/ GM-Tg-cynog-T75476-Ab-2; GM-Tg-felg-T75476-Ab-1/ GM-Tg-felg-T75476-Ab-2; GM-Tg-cang-T75476-Ab-1/ GM-Tg-cang-T75476-Ab-2; GM-Tg-bovg-T75476-Ab-1/ GM-Tg-bovg-T75476-Ab-2; GM-Tg-equg-T75476-Ab-1/ GM-Tg-equg-T75476-Ab-2 |
| Products Name | Anti-MYD88 monoclonal antibody |
| Format | mab |
| Target Name | MYD88 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MYD88 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T75476-Ag-1 | Recombinant multi-species MYD88/ MYD88D protein |
| ORF Viral Vector | vGMLV000373 | human MYD88 Lentivirus particle |
| ORF Viral Vector | pGMLV000373 | human MYD88 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001937 | mouse Myd88 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001937 | mouse Myd88 Lentivirus particle |
Target information
| Target ID | GM-T75476 |
| Target Name | MYD88 |
| Gene ID | 4615,17874,301059,696494,477024,101087092,444881,100053940 |
| Gene Symbol and Synonyms | IMD68,MYD88,MYD88D,WM1 |
| Uniprot Accession | Q99836,Q6Y1S1,B3Y683,Q599T9 |
| Uniprot Entry Name | MYD88_HUMAN,MYD88_MACMU,MYD88_RAT,MYD88_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000172936 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: MYD88, gene name: MYD88, also named as MYD88D. This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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