Anti-SMAD9 monoclonal antibody

Pre-made anti-SMAD9 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SMAD9/SMAD9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T75077-Ab-1/ GM-Tg-hg-T75077-Ab-2Anti-Human SMAD9 monoclonal antibodyHuman
GM-Tg-rg-T75077-Ab-1/ GM-Tg-rg-T75077-Ab-2Anti-Rat SMAD9 monoclonal antibodyRat
GM-Tg-mg-T75077-Ab-1/ GM-Tg-mg-T75077-Ab-2Anti-Mouse SMAD9 monoclonal antibodyMouse
GM-Tg-cynog-T75077-Ab-1/ GM-Tg-cynog-T75077-Ab-2Anti-Cynomolgus/ Rhesus macaque SMAD9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T75077-Ab-1/ GM-Tg-felg-T75077-Ab-2Anti-Feline SMAD9 monoclonal antibodyFeline
GM-Tg-cang-T75077-Ab-1/ GM-Tg-cang-T75077-Ab-2Anti-Canine SMAD9 monoclonal antibodyCanine
GM-Tg-bovg-T75077-Ab-1/ GM-Tg-bovg-T75077-Ab-2Anti-Bovine SMAD9 monoclonal antibodyBovine
GM-Tg-equg-T75077-Ab-1/ GM-Tg-equg-T75077-Ab-2Anti-Equine SMAD9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T75077-Ab-1/ GM-Tg-hg-T75077-Ab-2; GM-Tg-rg-T75077-Ab-1/ GM-Tg-rg-T75077-Ab-2;
GM-Tg-mg-T75077-Ab-1/ GM-Tg-mg-T75077-Ab-2; GM-Tg-cynog-T75077-Ab-1/ GM-Tg-cynog-T75077-Ab-2;
GM-Tg-felg-T75077-Ab-1/ GM-Tg-felg-T75077-Ab-2; GM-Tg-cang-T75077-Ab-1/ GM-Tg-cang-T75077-Ab-2;
GM-Tg-bovg-T75077-Ab-1/ GM-Tg-bovg-T75077-Ab-2; GM-Tg-equg-T75077-Ab-1/ GM-Tg-equg-T75077-Ab-2
Products NameAnti-SMAD9 monoclonal antibody
Formatmab
Target NameSMAD9
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SMAD9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T75077-Ag-1Recombinant multi-species SMAD9/ MADH6/ MADH9 protein
    CytokineGM-Tg-g-T75077-Ag-1SMAD family member 9 (SMAD9) protein
    ORF Viral VectorvGMLP003301human SMAD9 Lentivirus particle
    ORF Viral VectorpGMLP003301human SMAD9 Lentivirus plasmid


    Target information

    Target IDGM-T75077
    Target NameSMAD9
    Gene ID4093,55994,85435,694572,486006,101085942,540806,100062493
    Gene Symbol and SynonymsMADH6,Madh8,MADH9,PPH2,SMAD8,SMAD8/9,SMAD8A,SMAD8B,SMAD9
    Uniprot AccessionO15198,O54835
    Uniprot Entry NameSMAD9_HUMAN,SMAD9_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target, Cytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000120693
    Target ClassificationN/A

    The target: SMAD9, gene name: SMAD9, also named as MADH6, MADH9, PPH2, SMAD8, SMAD8/9, SMAD8A, SMAD8B. The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.