Anti-EPHB2/ CAPB/ DRT monoclonal antibody

Anti-EPHB2/ CAPB/ DRT antibody for FACS & in-vivo assay

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Target information

The target: EPHB2, gene name: EPHB2, also named as CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5. This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015].

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