Anti-GART monoclonal antibody
Pre-made anti-GART monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T72042-Ab-1/ GM-Tg-hg-T72042-Ab-2 | Anti-Human GART monoclonal antibody | Human |
GM-Tg-rg-T72042-Ab-1/ GM-Tg-rg-T72042-Ab-2 | Anti-Rat GART monoclonal antibody | Rat |
GM-Tg-mg-T72042-Ab-1/ GM-Tg-mg-T72042-Ab-2 | Anti-Mouse GART monoclonal antibody | Mouse |
GM-Tg-cynog-T72042-Ab-1/ GM-Tg-cynog-T72042-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GART monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T72042-Ab-1/ GM-Tg-felg-T72042-Ab-2 | Anti-Feline GART monoclonal antibody | Feline |
GM-Tg-cang-T72042-Ab-1/ GM-Tg-cang-T72042-Ab-2 | Anti-Canine GART monoclonal antibody | Canine |
GM-Tg-bovg-T72042-Ab-1/ GM-Tg-bovg-T72042-Ab-2 | Anti-Bovine GART monoclonal antibody | Bovine |
GM-Tg-equg-T72042-Ab-1/ GM-Tg-equg-T72042-Ab-2 | Anti-Equine GART monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T72042-Ab-1/ GM-Tg-hg-T72042-Ab-2; GM-Tg-rg-T72042-Ab-1/ GM-Tg-rg-T72042-Ab-2; GM-Tg-mg-T72042-Ab-1/ GM-Tg-mg-T72042-Ab-2; GM-Tg-cynog-T72042-Ab-1/ GM-Tg-cynog-T72042-Ab-2; GM-Tg-felg-T72042-Ab-1/ GM-Tg-felg-T72042-Ab-2; GM-Tg-cang-T72042-Ab-1/ GM-Tg-cang-T72042-Ab-2; GM-Tg-bovg-T72042-Ab-1/ GM-Tg-bovg-T72042-Ab-2; GM-Tg-equg-T72042-Ab-1/ GM-Tg-equg-T72042-Ab-2 |
Products Name | Anti-GART monoclonal antibody |
Format | mab |
Target Name | GART |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-GART monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T72042-Ag-1 | Recombinant multi-species PUR2/ GART/ AIRS protein |
Target information
Target ID | GM-T72042 |
Target Name | GART |
Gene ID | 2618,14450,288259,704926,487740,101087772,281183,100052316 |
Gene Symbol and Synonyms | AIRS,Gaps,GARS,GART,GARTF,LOC487740,PAIS,PGFT,PRGS |
Uniprot Accession | P22102,Q59A32 |
Uniprot Entry Name | PUR2_HUMAN,PUR2_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000159131 |
Target Classification | N/A |
The target: GART, gene name: GART, also named as AIRS, GARSF, PAIS, PGFT, PRGS, GART. The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.