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Anti-FGF10 monoclonal antibody
Anti-FGF10 antibody for FACS & in-vivo assay
Go to FGF10/FGF10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T62763-Ab-1/ GM-Tg-hg-T62763-Ab-2 | Anti-Human FGF10 monoclonal antibody | Human |
| GM-Tg-rg-T62763-Ab-1/ GM-Tg-rg-T62763-Ab-2 | Anti-Rat FGF10 monoclonal antibody | Rat |
| GM-Tg-mg-T62763-Ab-1/ GM-Tg-mg-T62763-Ab-2 | Anti-Mouse FGF10 monoclonal antibody | Mouse |
| GM-Tg-cynog-T62763-Ab-1/ GM-Tg-cynog-T62763-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T62763-Ab-1/ GM-Tg-felg-T62763-Ab-2 | Anti-Feline FGF10 monoclonal antibody | Feline |
| GM-Tg-cang-T62763-Ab-1/ GM-Tg-cang-T62763-Ab-2 | Anti-Canine FGF10 monoclonal antibody | Canine |
| GM-Tg-bovg-T62763-Ab-1/ GM-Tg-bovg-T62763-Ab-2 | Anti-Bovine FGF10 monoclonal antibody | Bovine |
| GM-Tg-equg-T62763-Ab-1/ GM-Tg-equg-T62763-Ab-2 | Anti-Equine FGF10 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T62763-Ab-1/ GM-Tg-hg-T62763-Ab-2; GM-Tg-rg-T62763-Ab-1/ GM-Tg-rg-T62763-Ab-2; GM-Tg-mg-T62763-Ab-1/ GM-Tg-mg-T62763-Ab-2; GM-Tg-cynog-T62763-Ab-1/ GM-Tg-cynog-T62763-Ab-2; GM-Tg-felg-T62763-Ab-1/ GM-Tg-felg-T62763-Ab-2; GM-Tg-cang-T62763-Ab-1/ GM-Tg-cang-T62763-Ab-2; GM-Tg-bovg-T62763-Ab-1/ GM-Tg-bovg-T62763-Ab-2; GM-Tg-equg-T62763-Ab-1/ GM-Tg-equg-T62763-Ab-2 |
| Products Name | Anti-FGF10 monoclonal antibody |
| Format | mab |
| Target Name | FGF10 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FGF10 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T62763-Ag-1 | fibroblast growth factor 10 (FGF10) protein |
| ORF Viral Vector | pGMLP004179 | human FGF10 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004179 | human FGF10 Lentivirus particle |
| ORF Viral Vector | pGMLPm003476 | mouse Fgf10 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003476 | mouse Fgf10 Lentivirus particle |
Target information
| Target ID | GM-T62763 |
| Target Name | FGF10 |
| Gene ID | 2255,14165,25443,701584,612454,101090489,326285,100052655 |
| Gene Symbol and Synonyms | AEY17,Fgf-10,FGF10,Fgf5a,Gsfaey17,LADD3 |
| Uniprot Accession | O15520,P70492 |
| Uniprot Entry Name | FGF10_HUMAN,FGF10_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000070193 |
| Target Classification | N/A |
The target: FGF10, gene name: FGF10, also named as . The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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