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Anti-PD2R2/ PTGDR2/ CD294 monoclonal antibody
Anti-PD2R2/ PTGDR2/ CD294 antibody for FACS & in-vivo assay
Go to PTGDR2/PTGDR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T61722-Ab-1/ GM-Tg-hg-T61722-Ab-2 | Anti-Human PTGDR2 monoclonal antibody | Human |
| GM-Tg-rg-T61722-Ab-1/ GM-Tg-rg-T61722-Ab-2 | Anti-Rat PTGDR2 monoclonal antibody | Rat |
| GM-Tg-mg-T61722-Ab-1/ GM-Tg-mg-T61722-Ab-2 | Anti-Mouse PTGDR2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T61722-Ab-1/ GM-Tg-cynog-T61722-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PTGDR2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T61722-Ab-1/ GM-Tg-felg-T61722-Ab-2 | Anti-Feline PTGDR2 monoclonal antibody | Feline |
| GM-Tg-cang-T61722-Ab-1/ GM-Tg-cang-T61722-Ab-2 | Anti-Canine PTGDR2 monoclonal antibody | Canine |
| GM-Tg-bovg-T61722-Ab-1/ GM-Tg-bovg-T61722-Ab-2 | Anti-Bovine PTGDR2 monoclonal antibody | Bovine |
| GM-Tg-equg-T61722-Ab-1/ GM-Tg-equg-T61722-Ab-2 | Anti-Equine PTGDR2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T61722-Ab-1/ GM-Tg-hg-T61722-Ab-2; GM-Tg-rg-T61722-Ab-1/ GM-Tg-rg-T61722-Ab-2; GM-Tg-mg-T61722-Ab-1/ GM-Tg-mg-T61722-Ab-2; GM-Tg-cynog-T61722-Ab-1/ GM-Tg-cynog-T61722-Ab-2; GM-Tg-felg-T61722-Ab-1/ GM-Tg-felg-T61722-Ab-2; GM-Tg-cang-T61722-Ab-1/ GM-Tg-cang-T61722-Ab-2; GM-Tg-bovg-T61722-Ab-1/ GM-Tg-bovg-T61722-Ab-2; GM-Tg-equg-T61722-Ab-1/ GM-Tg-equg-T61722-Ab-2 |
| Products Name | Anti-PTGDR2 monoclonal antibody |
| Format | mab |
| Target Name | PTGDR2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PTGDR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PD2R2/ PTGDR2/ CD294 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004450 | human PTGDR2 Lentivirus particle |
| ORF Viral Vector | pGMLP004450 | human PTGDR2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004397 | mouse Ptgdr2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004397 | mouse Ptgdr2 Lentivirus particle |
Target information
| Target ID | GM-T61722 |
| Target Name | PTGDR2 |
| Gene ID | 11251,14764,309212,695853,483805,101081756,337885,100061935 |
| Gene Symbol and Synonyms | CD294,CRTH2,DL1R,DP2,GPR44,Grp45,PTGDR2 |
| Uniprot Accession | Q9Y5Y4,Q6XKD3 |
| Uniprot Entry Name | PD2R2_HUMAN,PD2R2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000183134 |
| Target Classification | GPCR |
The target: PTGDR2, gene name: PTGDR2, also named as CD294, CRTH2, DL1R, DP2, GPR44. This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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