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Anti-KDM5B monoclonal antibody
Pre-made anti-KDM5B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to KDM5B/KDM5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T56871-Ab-1/ GM-Tg-hg-T56871-Ab-2 | Anti-Human KDM5B monoclonal antibody | Human |
| GM-Tg-rg-T56871-Ab-1/ GM-Tg-rg-T56871-Ab-2 | Anti-Rat KDM5B monoclonal antibody | Rat |
| GM-Tg-mg-T56871-Ab-1/ GM-Tg-mg-T56871-Ab-2 | Anti-Mouse KDM5B monoclonal antibody | Mouse |
| GM-Tg-cynog-T56871-Ab-1/ GM-Tg-cynog-T56871-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KDM5B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T56871-Ab-1/ GM-Tg-felg-T56871-Ab-2 | Anti-Feline KDM5B monoclonal antibody | Feline |
| GM-Tg-cang-T56871-Ab-1/ GM-Tg-cang-T56871-Ab-2 | Anti-Canine KDM5B monoclonal antibody | Canine |
| GM-Tg-bovg-T56871-Ab-1/ GM-Tg-bovg-T56871-Ab-2 | Anti-Bovine KDM5B monoclonal antibody | Bovine |
| GM-Tg-equg-T56871-Ab-1/ GM-Tg-equg-T56871-Ab-2 | Anti-Equine KDM5B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T56871-Ab-1/ GM-Tg-hg-T56871-Ab-2; GM-Tg-rg-T56871-Ab-1/ GM-Tg-rg-T56871-Ab-2; GM-Tg-mg-T56871-Ab-1/ GM-Tg-mg-T56871-Ab-2; GM-Tg-cynog-T56871-Ab-1/ GM-Tg-cynog-T56871-Ab-2; GM-Tg-felg-T56871-Ab-1/ GM-Tg-felg-T56871-Ab-2; GM-Tg-cang-T56871-Ab-1/ GM-Tg-cang-T56871-Ab-2; GM-Tg-bovg-T56871-Ab-1/ GM-Tg-bovg-T56871-Ab-2; GM-Tg-equg-T56871-Ab-1/ GM-Tg-equg-T56871-Ab-2 |
| Products Name | Anti-KDM5B monoclonal antibody |
| Format | mab |
| Target Name | KDM5B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KDM5B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T56871-Ag-1 | Recombinant multi-species KDM5B/ CT31/ JARID1B protein |
Target information
| Target ID | GM-T56871 |
| Target Name | KDM5B |
| Gene ID | 10765,75605,304809,706437,479999,101101609,540633,100064707 |
| Gene Symbol and Synonyms | 2010009J12Rik,2210016I17Rik,CT31,D1Ertd202e,JARID1B,KDM5B,mKIAA4034,MRT65,PLU-1,PLU1,PPP1R98,PUT1,Rb-Bp2,RBBP2H1A,RBP2-H1,RGD1565602 |
| Uniprot Accession | Q9UGL1 |
| Uniprot Entry Name | KDM5B_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000117139 |
| Target Classification | N/A |
The target: KDM5B, gene name: KDM5B, also named as CT31, JARID1B, MRT65, PLU-1, PLU1, PPP1R98, PUT1, RBBP2H1A, RBP2-H1. This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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