Anti-CTL4/ SLC44A4/ C6orf29 monoclonal antibody

Anti-CTL4/ SLC44A4/ C6orf29 antibody for FACS & in-vivo assay

Target products collectionGo to SLC44A4/SLC44A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T56362-Ab-1/ GM-Tg-hg-T56362-Ab-2Anti-Human SLC44A4 monoclonal antibodyHuman
GM-Tg-rg-T56362-Ab-1/ GM-Tg-rg-T56362-Ab-2Anti-Rat SLC44A4 monoclonal antibodyRat
GM-Tg-mg-T56362-Ab-1/ GM-Tg-mg-T56362-Ab-2Anti-Mouse SLC44A4 monoclonal antibodyMouse
GM-Tg-cynog-T56362-Ab-1/ GM-Tg-cynog-T56362-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC44A4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T56362-Ab-1/ GM-Tg-felg-T56362-Ab-2Anti-Feline SLC44A4 monoclonal antibodyFeline
GM-Tg-cang-T56362-Ab-1/ GM-Tg-cang-T56362-Ab-2Anti-Canine SLC44A4 monoclonal antibodyCanine
GM-Tg-bovg-T56362-Ab-1/ GM-Tg-bovg-T56362-Ab-2Anti-Bovine SLC44A4 monoclonal antibodyBovine
GM-Tg-equg-T56362-Ab-1/ GM-Tg-equg-T56362-Ab-2Anti-Equine SLC44A4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T56362-Ab-1/ GM-Tg-hg-T56362-Ab-2; GM-Tg-rg-T56362-Ab-1/ GM-Tg-rg-T56362-Ab-2;
GM-Tg-mg-T56362-Ab-1/ GM-Tg-mg-T56362-Ab-2; GM-Tg-cynog-T56362-Ab-1/ GM-Tg-cynog-T56362-Ab-2;
GM-Tg-felg-T56362-Ab-1/ GM-Tg-felg-T56362-Ab-2; GM-Tg-cang-T56362-Ab-1/ GM-Tg-cang-T56362-Ab-2;
GM-Tg-bovg-T56362-Ab-1/ GM-Tg-bovg-T56362-Ab-2; GM-Tg-equg-T56362-Ab-1/ GM-Tg-equg-T56362-Ab-2
Products NameAnti-SLC44A4 monoclonal antibody
Formatmab
Target NameSLC44A4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC44A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CTL4/ SLC44A4/ C6orf29 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T56362
    Target NameSLC44A4
    Gene ID80736,70129,294255,715779,481718,101091535,520625,100051054
    Gene Symbol and Synonyms2210409B01Rik,C6orf29,CTL4,DFNA72,hTPPT1,mTPPT1,NG22,SLC44A4,TPPT
    Uniprot AccessionQ53GD3,Q6MG71,A3KMY4
    Uniprot Entry NameCTL4_HUMAN,CTL4_RAT,CTL4_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000204385
    Target ClassificationN/A

    The target: SLC44A4, gene name: SLC44A4, also named as C6orf29, CTL4, DFNA72, NG22, TPPT, hTPPT1. The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.