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Anti-CXCL9/ CMK/ Humig functional antibody
Anti-CXCL9/ CMK/ Humig functional antibody for cell culture, ELISA & in-vivo assay
Go to CXCL9/CXCL9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T56349-Ab-1/ GM-Tg-hg-T56349-Ab-2 | Anti-Human CXCL9 monoclonal antibody | Human |
| GM-Tg-rg-T56349-Ab-1/ GM-Tg-rg-T56349-Ab-2 | Anti-Rat CXCL9 monoclonal antibody | Rat |
| GM-Tg-mg-T56349-Ab-1/ GM-Tg-mg-T56349-Ab-2 | Anti-Mouse CXCL9 monoclonal antibody | Mouse |
| GM-Tg-cynog-T56349-Ab-1/ GM-Tg-cynog-T56349-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CXCL9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T56349-Ab-1/ GM-Tg-felg-T56349-Ab-2 | Anti-Feline CXCL9 monoclonal antibody | Feline |
| GM-Tg-cang-T56349-Ab-1/ GM-Tg-cang-T56349-Ab-2 | Anti-Canine CXCL9 monoclonal antibody | Canine |
| GM-Tg-bovg-T56349-Ab-1/ GM-Tg-bovg-T56349-Ab-2 | Anti-Bovine CXCL9 monoclonal antibody | Bovine |
| GM-Tg-equg-T56349-Ab-1/ GM-Tg-equg-T56349-Ab-2 | Anti-Equine CXCL9 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T56349-Ab-1/ GM-Tg-hg-T56349-Ab-2; GM-Tg-rg-T56349-Ab-1/ GM-Tg-rg-T56349-Ab-2; GM-Tg-mg-T56349-Ab-1/ GM-Tg-mg-T56349-Ab-2; GM-Tg-cynog-T56349-Ab-1/ GM-Tg-cynog-T56349-Ab-2; GM-Tg-felg-T56349-Ab-1/ GM-Tg-felg-T56349-Ab-2; GM-Tg-cang-T56349-Ab-1/ GM-Tg-cang-T56349-Ab-2; GM-Tg-bovg-T56349-Ab-1/ GM-Tg-bovg-T56349-Ab-2; GM-Tg-equg-T56349-Ab-1/ GM-Tg-equg-T56349-Ab-2 |
| Products Name | Anti-CXCL9 monoclonal antibody |
| Format | mab |
| Target Name | CXCL9 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CXCL9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T56349-Ag-1 | Recombinant multi-species CXCL9/ CMK/ Humig protein |
| Cytokine | GM-Tg-g-T56349-Ag-1 | chemokine (C-X-C motif) ligand 9 (CXCL9) protein |
| ORF Viral Vector | vGMLP002749 | human CXCL9 Lentivirus particle |
| ORF Viral Vector | pGMLP002749 | human CXCL9 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000377 | house mouse Cxcl9 AAV plasmid |
| ORF Viral Vector | pGMLPm000565 | mouse Cxcl9 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000377 | house mouse Cxcl9 AAV particle |
| ORF Viral Vector | vGMLPm000565 | mouse Cxcl9 Lentivirus particle |
Target information
| Target ID | GM-T56349 |
| Target Name | CXCL9 |
| Gene ID | 4283,17329,246759,574336,101100388,513990,100057927 |
| Gene Symbol and Synonyms | CMK,crg-10,CXCL9,Humig,MIG,MuMIG,SCYB9 |
| Uniprot Accession | Q07325,A9QWP9 |
| Uniprot Entry Name | CXCL9_HUMAN,CXCL9_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
| Disease | Hyperacute Allograft Rejection, Complications of kidney transplant, Kidney transplant rejection |
| Gene Ensembl | ENSG00000138755 |
| Target Classification | Checkpoint-Immuno Oncology |
The target: CXCL9, gene name: CXCL9, also named as CMK, Humig, MIG, SCYB9, crg-10. This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded is thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Aug 2020].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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