Anti-LIPE monoclonal antibody

Pre-made anti-LIPE monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to LIPE/LIPE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T55689-Ab-1/ GM-Tg-hg-T55689-Ab-2Anti-Human LIPE monoclonal antibodyHuman
GM-Tg-rg-T55689-Ab-1/ GM-Tg-rg-T55689-Ab-2Anti-Rat LIPE monoclonal antibodyRat
GM-Tg-mg-T55689-Ab-1/ GM-Tg-mg-T55689-Ab-2Anti-Mouse LIPE monoclonal antibodyMouse
GM-Tg-cynog-T55689-Ab-1/ GM-Tg-cynog-T55689-Ab-2Anti-Cynomolgus/ Rhesus macaque LIPE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T55689-Ab-1/ GM-Tg-felg-T55689-Ab-2Anti-Feline LIPE monoclonal antibodyFeline
GM-Tg-cang-T55689-Ab-1/ GM-Tg-cang-T55689-Ab-2Anti-Canine LIPE monoclonal antibodyCanine
GM-Tg-bovg-T55689-Ab-1/ GM-Tg-bovg-T55689-Ab-2Anti-Bovine LIPE monoclonal antibodyBovine
GM-Tg-equg-T55689-Ab-1/ GM-Tg-equg-T55689-Ab-2Anti-Equine LIPE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T55689-Ab-1/ GM-Tg-hg-T55689-Ab-2; GM-Tg-rg-T55689-Ab-1/ GM-Tg-rg-T55689-Ab-2;
GM-Tg-mg-T55689-Ab-1/ GM-Tg-mg-T55689-Ab-2; GM-Tg-cynog-T55689-Ab-1/ GM-Tg-cynog-T55689-Ab-2;
GM-Tg-felg-T55689-Ab-1/ GM-Tg-felg-T55689-Ab-2; GM-Tg-cang-T55689-Ab-1/ GM-Tg-cang-T55689-Ab-2;
GM-Tg-bovg-T55689-Ab-1/ GM-Tg-bovg-T55689-Ab-2; GM-Tg-equg-T55689-Ab-1/ GM-Tg-equg-T55689-Ab-2
Products NameAnti-LIPE monoclonal antibody
Formatmab
Target NameLIPE
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-LIPE monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T55689-Ag-1Recombinant multi-species LIPS/ LIPE/ AOMS4 protein


    Target information

    Target IDGM-T55689
    Target NameLIPE
    Gene ID3991,16890,25330,707997,403607,751818,286879,100069598
    Gene Symbol and Synonyms4933403G17Rik,AOMS4,FPLD6,HSL,LHS,LIPE,REH
    Uniprot AccessionQ05469,P15304,P16386
    Uniprot Entry NameLIPS_HUMAN,LIPS_RAT,LIPS_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000079435
    Target ClassificationN/A

    The target: LIPE, gene name: LIPE, also named as AOMS4, FPLD6, HSL, LHS. The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.