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Anti-ASIC1/ ACCN2/ ASIC monoclonal antibody
Anti-ASIC1/ ACCN2/ ASIC antibody for FACS & in-vivo assay
Go to ASIC1/ASIC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T55094-Ab-1/ GM-Tg-hg-T55094-Ab-2 | Anti-Human ASIC1 monoclonal antibody | Human |
| GM-Tg-rg-T55094-Ab-1/ GM-Tg-rg-T55094-Ab-2 | Anti-Rat ASIC1 monoclonal antibody | Rat |
| GM-Tg-mg-T55094-Ab-1/ GM-Tg-mg-T55094-Ab-2 | Anti-Mouse ASIC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T55094-Ab-1/ GM-Tg-cynog-T55094-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ASIC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T55094-Ab-1/ GM-Tg-felg-T55094-Ab-2 | Anti-Feline ASIC1 monoclonal antibody | Feline |
| GM-Tg-cang-T55094-Ab-1/ GM-Tg-cang-T55094-Ab-2 | Anti-Canine ASIC1 monoclonal antibody | Canine |
| GM-Tg-bovg-T55094-Ab-1/ GM-Tg-bovg-T55094-Ab-2 | Anti-Bovine ASIC1 monoclonal antibody | Bovine |
| GM-Tg-equg-T55094-Ab-1/ GM-Tg-equg-T55094-Ab-2 | Anti-Equine ASIC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T55094-Ab-1/ GM-Tg-hg-T55094-Ab-2; GM-Tg-rg-T55094-Ab-1/ GM-Tg-rg-T55094-Ab-2; GM-Tg-mg-T55094-Ab-1/ GM-Tg-mg-T55094-Ab-2; GM-Tg-cynog-T55094-Ab-1/ GM-Tg-cynog-T55094-Ab-2; GM-Tg-felg-T55094-Ab-1/ GM-Tg-felg-T55094-Ab-2; GM-Tg-cang-T55094-Ab-1/ GM-Tg-cang-T55094-Ab-2; GM-Tg-bovg-T55094-Ab-1/ GM-Tg-bovg-T55094-Ab-2; GM-Tg-equg-T55094-Ab-1/ GM-Tg-equg-T55094-Ab-2 |
| Products Name | Anti-ASIC1 monoclonal antibody |
| Format | mab |
| Target Name | ASIC1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ASIC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ASIC1/ ACCN2/ ASIC VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLV000085 | human ASIC1 Lentivirus particle |
| ORF Viral Vector | pGMLP003358 | human ASIC1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000085 | human ASIC1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003358 | human ASIC1 Lentivirus particle |
| ORF Viral Vector | pGMLPm004382 | mouse Asic1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004382 | mouse Asic1 Lentivirus particle |
Target information
| Target ID | GM-T55094 |
| Target Name | ASIC1 |
| Gene ID | 41,11419,79123,713320,477612,101085729,538244,100630368 |
| Gene Symbol and Synonyms | ACCN2,ASIC,ASIC1,ASIC1a,ASIC1b,B530003N02Rik,BNaC2 |
| Uniprot Accession | P78348,P55926 |
| Uniprot Entry Name | ASIC1_HUMAN,ASIC1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000110881 |
| Target Classification | N/A |
The target: ASIC1, gene name: ASIC1, also named as ACCN2, ASIC, BNaC2. This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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