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Anti-SC5A1/ SGLT1/ SLC5A1 monoclonal antibody
Anti-SC5A1/ SGLT1/ SLC5A1 antibody for FACS & in-vivo assay
Go to SGLT1/SLC5A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T54771-Ab-1/ GM-Tg-hg-T54771-Ab-2 | Anti-Human SGLT1/SLC5A1 monoclonal antibody | Human |
| GM-Tg-rg-T54771-Ab-1/ GM-Tg-rg-T54771-Ab-2 | Anti-Rat SGLT1/SLC5A1 monoclonal antibody | Rat |
| GM-Tg-mg-T54771-Ab-1/ GM-Tg-mg-T54771-Ab-2 | Anti-Mouse SGLT1/SLC5A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T54771-Ab-1/ GM-Tg-cynog-T54771-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SGLT1/SLC5A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T54771-Ab-1/ GM-Tg-felg-T54771-Ab-2 | Anti-Feline SGLT1/SLC5A1 monoclonal antibody | Feline |
| GM-Tg-cang-T54771-Ab-1/ GM-Tg-cang-T54771-Ab-2 | Anti-Canine SGLT1/SLC5A1 monoclonal antibody | Canine |
| GM-Tg-bovg-T54771-Ab-1/ GM-Tg-bovg-T54771-Ab-2 | Anti-Bovine SGLT1/SLC5A1 monoclonal antibody | Bovine |
| GM-Tg-equg-T54771-Ab-1/ GM-Tg-equg-T54771-Ab-2 | Anti-Equine SGLT1/SLC5A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T54771-Ab-1/ GM-Tg-hg-T54771-Ab-2; GM-Tg-rg-T54771-Ab-1/ GM-Tg-rg-T54771-Ab-2; GM-Tg-mg-T54771-Ab-1/ GM-Tg-mg-T54771-Ab-2; GM-Tg-cynog-T54771-Ab-1/ GM-Tg-cynog-T54771-Ab-2; GM-Tg-felg-T54771-Ab-1/ GM-Tg-felg-T54771-Ab-2; GM-Tg-cang-T54771-Ab-1/ GM-Tg-cang-T54771-Ab-2; GM-Tg-bovg-T54771-Ab-1/ GM-Tg-bovg-T54771-Ab-2; GM-Tg-equg-T54771-Ab-1/ GM-Tg-equg-T54771-Ab-2 |
| Products Name | Anti-SGLT1/SLC5A1 monoclonal antibody |
| Format | mab |
| Target Name | SGLT1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SGLT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SC5A1/ SGLT1/ SLC5A1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001849 | human SLC5A1 Lentivirus particle |
| ORF Viral Vector | pGMLP001849 | human SLC5A1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000464 | human SLC5A1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000464 | human SLC5A1 Lentivirus particle |
Target information
| Target ID | GM-T54771 |
| Target Name | SGLT1 |
| Gene ID | 6523,20537,25552,717070,492299,100500739,282361,100033952 |
| Gene Symbol and Synonyms | D22S675,NAGT,SGLT-1,SGLT1,SGLT1a,SLC5A1 |
| Uniprot Accession | P13866,P53790 |
| Uniprot Entry Name | SC5A1_HUMAN,SC5A1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000100170 |
| Target Classification | N/A |
The target: SGLT1, gene name: SLC5A1, also named as D22S675, NAGT, SGLT1. This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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