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Anti-NAMPT/ 1110035O14Rik/ PBEF monoclonal antibody
Anti-NAMPT/ 1110035O14Rik/ PBEF antibody for FACS & in-vivo assay
Go to NAMPT/NAMPT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T54582-Ab-1/ GM-Tg-hg-T54582-Ab-2 | Anti-Human NAMPT monoclonal antibody | Human |
| GM-Tg-rg-T54582-Ab-1/ GM-Tg-rg-T54582-Ab-2 | Anti-Rat NAMPT monoclonal antibody | Rat |
| GM-Tg-mg-T54582-Ab-1/ GM-Tg-mg-T54582-Ab-2 | Anti-Mouse NAMPT monoclonal antibody | Mouse |
| GM-Tg-cynog-T54582-Ab-1/ GM-Tg-cynog-T54582-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NAMPT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T54582-Ab-1/ GM-Tg-felg-T54582-Ab-2 | Anti-Feline NAMPT monoclonal antibody | Feline |
| GM-Tg-cang-T54582-Ab-1/ GM-Tg-cang-T54582-Ab-2 | Anti-Canine NAMPT monoclonal antibody | Canine |
| GM-Tg-bovg-T54582-Ab-1/ GM-Tg-bovg-T54582-Ab-2 | Anti-Bovine NAMPT monoclonal antibody | Bovine |
| GM-Tg-equg-T54582-Ab-1/ GM-Tg-equg-T54582-Ab-2 | Anti-Equine NAMPT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T54582-Ab-1/ GM-Tg-hg-T54582-Ab-2; GM-Tg-rg-T54582-Ab-1/ GM-Tg-rg-T54582-Ab-2; GM-Tg-mg-T54582-Ab-1/ GM-Tg-mg-T54582-Ab-2; GM-Tg-cynog-T54582-Ab-1/ GM-Tg-cynog-T54582-Ab-2; GM-Tg-felg-T54582-Ab-1/ GM-Tg-felg-T54582-Ab-2; GM-Tg-cang-T54582-Ab-1/ GM-Tg-cang-T54582-Ab-2; GM-Tg-bovg-T54582-Ab-1/ GM-Tg-bovg-T54582-Ab-2; GM-Tg-equg-T54582-Ab-1/ GM-Tg-equg-T54582-Ab-2 |
| Products Name | Anti-NAMPT monoclonal antibody |
| Format | mab |
| Target Name | NAMPT |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NAMPT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NAMPT/ 1110035O14Rik/ PBEF VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T54582-Ag-1 | nicotinamide phosphoribosyltransferase (NAMPT) protein |
| ORF Viral Vector | pGMAAV000079 | mouse Nampt AAV plasmid |
| ORF Viral Vector | vGMAAV000079 | mouse Nampt AAV particle |
Target information
| Target ID | GM-T54582 |
| Target Name | NAMPT |
| Gene ID | 10135,59027,297508,698609,100856598,101081370,520472,100059684 |
| Gene Symbol and Synonyms | 1110035O14Rik,NAmPRTase,NAMPT,PBEF,PBEF1,VF,VISFATIN |
| Uniprot Accession | P43490,Q80Z29 |
| Uniprot Entry Name | NAMPT_HUMAN,NAMPT_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000105835 |
| Target Classification | N/A |
The target: NAMPT, gene name: NAMPT, also named as 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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