Anti-FAP48 monoclonal antibody

Pre-made anti-FAP48 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FAP48/GLMN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T43817-Ab-1/ GM-Tg-hg-T43817-Ab-2Anti-Human FAP48/GLMN monoclonal antibodyHuman
GM-Tg-rg-T43817-Ab-1/ GM-Tg-rg-T43817-Ab-2Anti-Rat FAP48/GLMN monoclonal antibodyRat
GM-Tg-mg-T43817-Ab-1/ GM-Tg-mg-T43817-Ab-2Anti-Mouse FAP48/GLMN monoclonal antibodyMouse
GM-Tg-cynog-T43817-Ab-1/ GM-Tg-cynog-T43817-Ab-2Anti-Cynomolgus/ Rhesus macaque FAP48/GLMN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T43817-Ab-1/ GM-Tg-felg-T43817-Ab-2Anti-Feline FAP48/GLMN monoclonal antibodyFeline
GM-Tg-cang-T43817-Ab-1/ GM-Tg-cang-T43817-Ab-2Anti-Canine FAP48/GLMN monoclonal antibodyCanine
GM-Tg-bovg-T43817-Ab-1/ GM-Tg-bovg-T43817-Ab-2Anti-Bovine FAP48/GLMN monoclonal antibodyBovine
GM-Tg-equg-T43817-Ab-1/ GM-Tg-equg-T43817-Ab-2Anti-Equine FAP48/GLMN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T43817-Ab-1/ GM-Tg-hg-T43817-Ab-2; GM-Tg-rg-T43817-Ab-1/ GM-Tg-rg-T43817-Ab-2;
GM-Tg-mg-T43817-Ab-1/ GM-Tg-mg-T43817-Ab-2; GM-Tg-cynog-T43817-Ab-1/ GM-Tg-cynog-T43817-Ab-2;
GM-Tg-felg-T43817-Ab-1/ GM-Tg-felg-T43817-Ab-2; GM-Tg-cang-T43817-Ab-1/ GM-Tg-cang-T43817-Ab-2;
GM-Tg-bovg-T43817-Ab-1/ GM-Tg-bovg-T43817-Ab-2; GM-Tg-equg-T43817-Ab-1/ GM-Tg-equg-T43817-Ab-2
Products NameAnti-FAP48/GLMN monoclonal antibody
Formatmab
Target NameFAP48
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FAP48 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T43817-Ag-1Recombinant multi-species GLMN/ FAP48/ FAP protein


    Target information

    Target IDGM-T43817
    Target NameFAP48
    Gene ID11146,170823,289437,706249,479951,101086584,504211,100051435
    Gene Symbol and Synonyms9330160J16Rik,FAP,FAP48,FAP68,FKBPAP,GLML,GLMN,glomulin,GVM,VMGLOM
    Uniprot AccessionQ92990
    Uniprot Entry NameGLMN_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000174842
    Target ClassificationN/A

    The target: FAP48, gene name: GLMN, also named as FAP, FAP48, FAP68, FKBPAP, GLML, GVM, VMGLOM. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Multiple splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.