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Anti-EGFL7/ NEU1/ VE-STATIN functional antibody
Anti-EGFL7/ NEU1/ VE-STATIN functional antibody for cell culture, ELISA & in-vivo assay
Go to EGFL7/EGFL7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T40010-Ab-1/ GM-Tg-hg-T40010-Ab-2 | Anti-Human EGFL7 monoclonal antibody | Human |
| GM-Tg-rg-T40010-Ab-1/ GM-Tg-rg-T40010-Ab-2 | Anti-Rat EGFL7 monoclonal antibody | Rat |
| GM-Tg-mg-T40010-Ab-1/ GM-Tg-mg-T40010-Ab-2 | Anti-Mouse EGFL7 monoclonal antibody | Mouse |
| GM-Tg-cynog-T40010-Ab-1/ GM-Tg-cynog-T40010-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EGFL7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T40010-Ab-1/ GM-Tg-felg-T40010-Ab-2 | Anti-Feline EGFL7 monoclonal antibody | Feline |
| GM-Tg-cang-T40010-Ab-1/ GM-Tg-cang-T40010-Ab-2 | Anti-Canine EGFL7 monoclonal antibody | Canine |
| GM-Tg-bovg-T40010-Ab-1/ GM-Tg-bovg-T40010-Ab-2 | Anti-Bovine EGFL7 monoclonal antibody | Bovine |
| GM-Tg-equg-T40010-Ab-1/ GM-Tg-equg-T40010-Ab-2 | Anti-Equine EGFL7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T40010-Ab-1/ GM-Tg-hg-T40010-Ab-2; GM-Tg-rg-T40010-Ab-1/ GM-Tg-rg-T40010-Ab-2; GM-Tg-mg-T40010-Ab-1/ GM-Tg-mg-T40010-Ab-2; GM-Tg-cynog-T40010-Ab-1/ GM-Tg-cynog-T40010-Ab-2; GM-Tg-felg-T40010-Ab-1/ GM-Tg-felg-T40010-Ab-2; GM-Tg-cang-T40010-Ab-1/ GM-Tg-cang-T40010-Ab-2; GM-Tg-bovg-T40010-Ab-1/ GM-Tg-bovg-T40010-Ab-2; GM-Tg-equg-T40010-Ab-1/ GM-Tg-equg-T40010-Ab-2 |
| Products Name | Anti-EGFL7 monoclonal antibody |
| Format | mab |
| Target Name | EGFL7 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EGFL7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-428 | Pre-Made Parsatuzumab biosimilar, Whole mAb, Anti-EGFL7 Antibody: Anti-NEU1/VE-STATIN/ZNEU1 therapeutic antibody |
| Target Antigen | GM-Tg-g-T40010-Ag-1 | Recombinant multi-species EGFL7/ NEU1/ VE-STATIN protein |
| Cytokine | GM-Tg-g-T40010-Ag-1 | EGF-like-domain, multiple 7 (EGFL7) protein |
| ORF Viral Vector | pGMLP003495 | human EGFL7 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003495 | human EGFL7 Lentivirus particle |
| ORF Viral Vector | pGMLPm000363 | mouse Egfl7 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000363 | mouse Egfl7 Lentivirus particle |
Target information
| Target ID | GM-T40010 |
| Target Name | EGFL7 |
| Gene ID | 51162,353156,245963,709840,491250,101089659,613671,100066378 |
| Gene Symbol and Synonyms | EGFL7,NEU1,VE-STATIN,ZNEU1 |
| Uniprot Accession | Q9UHF1,Q6AZ60 |
| Uniprot Entry Name | EGFL7_HUMAN,EGFL7_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000172889 |
| Target Classification | N/A |
The target: EGFL7, gene name: EGFL7, also named as NEU1, VE-STATIN, ZNEU1. This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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