Anti-ANXA1/ PA2IP/ ANX1 monoclonal antibody

Anti-ANXA1/ PA2IP/ ANX1 antibody for FACS & in-vivo assay

Target products collectionGo to PA2IP/ANXA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T38161-Ab-1/ GM-Tg-hg-T38161-Ab-2Anti-Human PA2IP/ANXA1 monoclonal antibodyHuman
GM-Tg-rg-T38161-Ab-1/ GM-Tg-rg-T38161-Ab-2Anti-Rat PA2IP/ANXA1 monoclonal antibodyRat
GM-Tg-mg-T38161-Ab-1/ GM-Tg-mg-T38161-Ab-2Anti-Mouse PA2IP/ANXA1 monoclonal antibodyMouse
GM-Tg-cynog-T38161-Ab-1/ GM-Tg-cynog-T38161-Ab-2Anti-Cynomolgus/ Rhesus macaque PA2IP/ANXA1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T38161-Ab-1/ GM-Tg-felg-T38161-Ab-2Anti-Feline PA2IP/ANXA1 monoclonal antibodyFeline
GM-Tg-cang-T38161-Ab-1/ GM-Tg-cang-T38161-Ab-2Anti-Canine PA2IP/ANXA1 monoclonal antibodyCanine
GM-Tg-bovg-T38161-Ab-1/ GM-Tg-bovg-T38161-Ab-2Anti-Bovine PA2IP/ANXA1 monoclonal antibodyBovine
GM-Tg-equg-T38161-Ab-1/ GM-Tg-equg-T38161-Ab-2Anti-Equine PA2IP/ANXA1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T38161-Ab-1/ GM-Tg-hg-T38161-Ab-2; GM-Tg-rg-T38161-Ab-1/ GM-Tg-rg-T38161-Ab-2;
GM-Tg-mg-T38161-Ab-1/ GM-Tg-mg-T38161-Ab-2; GM-Tg-cynog-T38161-Ab-1/ GM-Tg-cynog-T38161-Ab-2;
GM-Tg-felg-T38161-Ab-1/ GM-Tg-felg-T38161-Ab-2; GM-Tg-cang-T38161-Ab-1/ GM-Tg-cang-T38161-Ab-2;
GM-Tg-bovg-T38161-Ab-1/ GM-Tg-bovg-T38161-Ab-2; GM-Tg-equg-T38161-Ab-1/ GM-Tg-equg-T38161-Ab-2
Products NameAnti-PA2IP/ANXA1 monoclonal antibody
Formatmab
Target NamePA2IP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PA2IP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ANXA1/ PA2IP/ ANX1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMAP000175Human ANXA1 Adenovirus particle
    ORF Viral VectorpGMAD000020human ANXA1 Adenovirus plasmid
    ORF Viral VectorpGMAD000418human ANXA1 Adenovirus plasmid
    ORF Viral VectorvGMAD000418human ANXA1 Adenovirus particle
    ORF Viral VectorvGMLV000465human ANXA1 Lentivirus particle
    ORF Viral VectorpGMLV000465human ANXA1 Lentivirus plasmid
    ORF Viral VectorvGMAD000020human ANXA1 Adenovirus particle
    ORF Viral VectorpGMAP000175Human ANXA1 Adenovirus plasmid
    ORF Viral VectorpGMLV000146mouse Anxa1 Lentivirus plasmid
    ORF Viral VectorpGMLV000523house mouse Anxa1 Lentivirus plasmid
    ORF Viral VectorvGMLV000146mouse Anxa1 Lentivirus particle
    ORF Viral VectorvGMLV000523house mouse Anxa1 Lentivirus particle


    Target information

    Target IDGM-T38161
    Target NamePA2IP
    Gene ID301,16952,25380,702946,476322,493875,327662,100033940
    Gene Symbol and SynonymsAnx-1,Anx-A1,ANX1,ANXA1,C430014K04Rik,Lpc-1,LPC1,p35
    Uniprot AccessionP04083,P07150,P46193,Q8HZM6
    Uniprot Entry NameANXA1_HUMAN,ANXA1_RAT,ANXA1_BOVIN,ANXA1_HORSE
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseLung Cancer, Glomerulonephritis
    Gene EnsemblENSG00000135046
    Target ClassificationN/A

    The target: PA2IP, gene name: ANXA1, also named as ANX1, LPC1. This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.