Anti-PAR1/ F2R/ CF2R monoclonal antibody
Anti-PAR1/ F2R/ CF2R antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T36483-Ab-1/ GM-Tg-hg-T36483-Ab-2 | Anti-Human F2R monoclonal antibody | Human |
GM-Tg-rg-T36483-Ab-1/ GM-Tg-rg-T36483-Ab-2 | Anti-Rat F2R monoclonal antibody | Rat |
GM-Tg-mg-T36483-Ab-1/ GM-Tg-mg-T36483-Ab-2 | Anti-Mouse F2R monoclonal antibody | Mouse |
GM-Tg-cynog-T36483-Ab-1/ GM-Tg-cynog-T36483-Ab-2 | Anti-Cynomolgus/ Rhesus macaque F2R monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T36483-Ab-1/ GM-Tg-felg-T36483-Ab-2 | Anti-Feline F2R monoclonal antibody | Feline |
GM-Tg-cang-T36483-Ab-1/ GM-Tg-cang-T36483-Ab-2 | Anti-Canine F2R monoclonal antibody | Canine |
GM-Tg-bovg-T36483-Ab-1/ GM-Tg-bovg-T36483-Ab-2 | Anti-Bovine F2R monoclonal antibody | Bovine |
GM-Tg-equg-T36483-Ab-1/ GM-Tg-equg-T36483-Ab-2 | Anti-Equine F2R monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T36483-Ab-1/ GM-Tg-hg-T36483-Ab-2; GM-Tg-rg-T36483-Ab-1/ GM-Tg-rg-T36483-Ab-2; GM-Tg-mg-T36483-Ab-1/ GM-Tg-mg-T36483-Ab-2; GM-Tg-cynog-T36483-Ab-1/ GM-Tg-cynog-T36483-Ab-2; GM-Tg-felg-T36483-Ab-1/ GM-Tg-felg-T36483-Ab-2; GM-Tg-cang-T36483-Ab-1/ GM-Tg-cang-T36483-Ab-2; GM-Tg-bovg-T36483-Ab-1/ GM-Tg-bovg-T36483-Ab-2; GM-Tg-equg-T36483-Ab-1/ GM-Tg-equg-T36483-Ab-2 |
Products Name | Anti-F2R monoclonal antibody |
Format | mab |
Target Name | F2R |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-F2R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species PAR1/ F2R/ CF2R VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLP003683 | human F2R Lentivirus particle |
ORF Viral Vector | pGMLP003683 | human F2R Lentivirus plasmid |
ORF Viral Vector | pGMLPm003837 | mouse F2r Lentivirus plasmid |
ORF Viral Vector | vGMLPm003837 | mouse F2r Lentivirus particle |
Target information
Target ID | GM-T36483 |
Target Name | F2R |
Gene ID | 2149,14062,25439,707370,488942,101100861,526585,100073278 |
Gene Symbol and Synonyms | CF2R,F2R,HTR,PAR-1,PAR1,ThrR,TR,TRGPC |
Uniprot Accession | P25116,P26824,A7YY44 |
Uniprot Entry Name | PAR1_HUMAN,PAR1_RAT,PAR1_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000181104 |
Target Classification | N/A |
The target: F2R, gene name: F2R, also named as CF2R, HTR, PAR-1, PAR1, TR. Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.