Anti-SO2B1/ SLCO2B1/ OATP-B monoclonal antibody

Anti-SO2B1/ SLCO2B1/ OATP-B antibody for FACS & in-vivo assay

Target products collectionGo to SLCO2B1/SLCO2B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T34064-Ab-1/ GM-Tg-hg-T34064-Ab-2Anti-Human SLCO2B1 monoclonal antibodyHuman
GM-Tg-rg-T34064-Ab-1/ GM-Tg-rg-T34064-Ab-2Anti-Rat SLCO2B1 monoclonal antibodyRat
GM-Tg-mg-T34064-Ab-1/ GM-Tg-mg-T34064-Ab-2Anti-Mouse SLCO2B1 monoclonal antibodyMouse
GM-Tg-cynog-T34064-Ab-1/ GM-Tg-cynog-T34064-Ab-2Anti-Cynomolgus/ Rhesus macaque SLCO2B1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T34064-Ab-1/ GM-Tg-felg-T34064-Ab-2Anti-Feline SLCO2B1 monoclonal antibodyFeline
GM-Tg-cang-T34064-Ab-1/ GM-Tg-cang-T34064-Ab-2Anti-Canine SLCO2B1 monoclonal antibodyCanine
GM-Tg-bovg-T34064-Ab-1/ GM-Tg-bovg-T34064-Ab-2Anti-Bovine SLCO2B1 monoclonal antibodyBovine
GM-Tg-equg-T34064-Ab-1/ GM-Tg-equg-T34064-Ab-2Anti-Equine SLCO2B1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T34064-Ab-1/ GM-Tg-hg-T34064-Ab-2; GM-Tg-rg-T34064-Ab-1/ GM-Tg-rg-T34064-Ab-2;
GM-Tg-mg-T34064-Ab-1/ GM-Tg-mg-T34064-Ab-2; GM-Tg-cynog-T34064-Ab-1/ GM-Tg-cynog-T34064-Ab-2;
GM-Tg-felg-T34064-Ab-1/ GM-Tg-felg-T34064-Ab-2; GM-Tg-cang-T34064-Ab-1/ GM-Tg-cang-T34064-Ab-2;
GM-Tg-bovg-T34064-Ab-1/ GM-Tg-bovg-T34064-Ab-2; GM-Tg-equg-T34064-Ab-1/ GM-Tg-equg-T34064-Ab-2
Products NameAnti-SLCO2B1 monoclonal antibody
Formatmab
Target NameSLCO2B1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLCO2B1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SO2B1/ SLCO2B1/ OATP-B VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLV000174human SLCO2B1 Lentivirus particle
    ORF Viral VectorpGMLV000174human SLCO2B1 Lentivirus plasmid


    Target information

    Target IDGM-T34064
    Target NameSLCO2B1
    Gene ID11309,101488,140860,694829,485192,101101333,317704,100009692
    Gene Symbol and Synonymsmoat1,OATP-B,OATP2B1,OATPB,SLC21A9,SLCO2B1
    Uniprot AccessionO94956,Q9JHI3
    Uniprot Entry NameSO2B1_HUMAN,SO2B1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000137491
    Target ClassificationN/A

    The target: SLCO2B1, gene name: SLCO2B1, also named as OATP-B, OATP2B1, OATPB, SLC21A9. This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.