Anti-ACE2 monoclonal antibody
The Alternative Names of target: ACE2,Angiotensin-converting enzyme 2,Angiotensin-converting enzyme homolog (ACEH), Angiotensin-converting enzyme-related carboxypeptidase (ACE-related carboxypeptidase), Metalloprotease MPROT15,ACEH
                                                                    Pre-made anti-ACE2 monoclonal antibody (mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
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(antibodies,
                                                                            antigen, VLP, mRNA, ORF viral vector, etc)
                                                                        
                                                                    
Product information
| Catalog No. | Product Name | Species Reactivity | 
|---|---|---|
| GM-Tg-hg-T27889-Ab-1/ GM-Tg-hg-T27889-Ab-2 | Anti-Human ACE2 monoclonal antibody | Human | 
| GM-Tg-rg-T27889-Ab-1/ GM-Tg-rg-T27889-Ab-2 | Anti-Rat ACE2 monoclonal antibody | Rat | 
| GM-Tg-mg-T27889-Ab-1/ GM-Tg-mg-T27889-Ab-2 | Anti-Mouse ACE2 monoclonal antibody | Mouse | 
| GM-Tg-cynog-T27889-Ab-1/ GM-Tg-cynog-T27889-Ab-2 | Anti-Cynomolgus/Rhesus macaque ACE2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 
| GM-Tg-felg-T27889-Ab-1/ GM-Tg-felg-T27889-Ab-2 | Anti-Feline ACE2 monoclonal antibody | Feline | 
| GM-Tg-cang-T27889-Ab-1/ GM-Tg-cang-T27889-Ab-2 | Anti-Canine ACE2 monoclonal antibody | Canine | 
| GM-Tg-bovg-T27889-Ab-1/ GM-Tg-bovg-T27889-Ab-2 | Anti-Bovine ACE2 monoclonal antibody | Bovine | 
| GM-Tg-equg-T27889-Ab-1/ GM-Tg-equg-T27889-Ab-2 | Anti-Equine ACE2 monoclonal antibody | Equine | 
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T27889-Ab-1/ GM-Tg-hg-T27889-Ab-2;
                                                                    GM-Tg-rg-T27889-Ab-1/ GM-Tg-rg-T27889-Ab-2; GM-Tg-mg-T27889-Ab-1/ GM-Tg-mg-T27889-Ab-2; GM-Tg-cynog-T27889-Ab-1/ GM-Tg-cynog-T27889-Ab-2; GM-Tg-felg-T27889-Ab-1/ GM-Tg-felg-T27889-Ab-2; GM-Tg-cang-T27889-Ab-1/ GM-Tg-cang-T27889-Ab-2; GM-Tg-bovg-T27889-Ab-1/ GM-Tg-bovg-T27889-Ab-2; GM-Tg-equg-T27889-Ab-1/ GM-Tg-equg-T27889-Ab-2 | 
| Products Name | Anti-ACE2 monoclonal antibody | 
| Format | mab | 
| Target Name | ACE2 | 
| Protein Sub-location | Transmembrane Protein | 
| Category of antibody | Therapeutics Target, Diagnostics Biomarker | 
| Derivation (species) | Mouse | 
| CH1+2+3 Isotype (Receptor identification) | IgG | 
| Type of Light Chain (VD-LC) | N/A | 
| Expression platform | Mammalian Expression | 
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. | 
| Tag | Fc | 
| Products description | Pre-made anti-ACE2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) | 
| Purity | Purity: ≥95% (SDS-PAGE) | 
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. | 
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2
                                                                    (PSB2,Confidential Ingredients) or PBS
                                                                    (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. | 
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. | 
Reference
Data/case study
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About Gmab

 
                                                                    
GMab, developed by GeneMedi, constitutes an
                                                                        advanced library of recombinant
                                                                        monoclonal antibodies, each meticulously
                                                                        designed to target specific molecular
                                                                        entities. Leveraging the sophisticated
                                                                        capabilities of GM’s Taurus™ and LIBRA™
                                                                        platforms, GMab synthesizes antibodies
                                                                        characterized by high binding affinity,
                                                                        exceptional physicochemical stability, and
                                                                        optimal developability profiles.
Through
                                                                        expression in mammalian cell lines, GMab has
                                                                        been established as a paradigmatic
                                                                        reference antibody. It holds significance in
                                                                        myriad domains of biological drug
                                                                        discovery, encompassing cellular cultivation,
                                                                        innovative assay methodologies,
                                                                        strategic animal model systematization, in-depth
                                                                        pharmacokinetic & pharmacodynamic
                                                                        (PK/PD) modeling, and intricate mechanism of
                                                                        action (MOA) investigations.
 
                
                 
             
         
         
                                             
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