Anti-SPTBN1 monoclonal antibody

Pre-made anti-SPTBN1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SPTBN1/SPTBN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T27826-Ab-1/ GM-Tg-hg-T27826-Ab-2Anti-Human SPTBN1 monoclonal antibodyHuman
GM-Tg-rg-T27826-Ab-1/ GM-Tg-rg-T27826-Ab-2Anti-Rat SPTBN1 monoclonal antibodyRat
GM-Tg-mg-T27826-Ab-1/ GM-Tg-mg-T27826-Ab-2Anti-Mouse SPTBN1 monoclonal antibodyMouse
GM-Tg-cynog-T27826-Ab-1/ GM-Tg-cynog-T27826-Ab-2Anti-Cynomolgus/ Rhesus macaque SPTBN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T27826-Ab-1/ GM-Tg-felg-T27826-Ab-2Anti-Feline SPTBN1 monoclonal antibodyFeline
GM-Tg-cang-T27826-Ab-1/ GM-Tg-cang-T27826-Ab-2Anti-Canine SPTBN1 monoclonal antibodyCanine
GM-Tg-bovg-T27826-Ab-1/ GM-Tg-bovg-T27826-Ab-2Anti-Bovine SPTBN1 monoclonal antibodyBovine
GM-Tg-equg-T27826-Ab-1/ GM-Tg-equg-T27826-Ab-2Anti-Equine SPTBN1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T27826-Ab-1/ GM-Tg-hg-T27826-Ab-2; GM-Tg-rg-T27826-Ab-1/ GM-Tg-rg-T27826-Ab-2;
GM-Tg-mg-T27826-Ab-1/ GM-Tg-mg-T27826-Ab-2; GM-Tg-cynog-T27826-Ab-1/ GM-Tg-cynog-T27826-Ab-2;
GM-Tg-felg-T27826-Ab-1/ GM-Tg-felg-T27826-Ab-2; GM-Tg-cang-T27826-Ab-1/ GM-Tg-cang-T27826-Ab-2;
GM-Tg-bovg-T27826-Ab-1/ GM-Tg-bovg-T27826-Ab-2; GM-Tg-equg-T27826-Ab-1/ GM-Tg-equg-T27826-Ab-2
Products NameAnti-SPTBN1 monoclonal antibody
Formatmab
Target NameSPTBN1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SPTBN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T27826-Ag-1Recombinant multi-species SPTB2/ SPTBN1/ ELF protein


    Target information

    Target IDGM-T27826
    Target NameSPTBN1
    Gene ID6711,20742,305614,716794,403743,101090509,526027,100052695
    Gene Symbol and Synonyms9930031C03Rik,betaSpII,DDISBA,ELF,elf1,elf3,HEL102,mKIAA4049,Spnb-2,Spnb1,Spnb2,SPTB2,SPTBN1
    Uniprot AccessionQ01082
    Uniprot Entry NameSPTB2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000115306
    Target ClassificationN/A

    The target: SPTBN1, gene name: SPTBN1, also named as ELF, HEL102, SPTB2, betaSpII. Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.