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Anti-CXL13/ CXCL13/ ANGIE functional antibody
Anti-CXL13/ CXCL13/ ANGIE functional antibody for cell culture, ELISA & in-vivo assay
Go to CXCL13/CXCL13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T27700-Ab-1/ GM-Tg-hg-T27700-Ab-2 | Anti-Human CXCL13 monoclonal antibody | Human |
| GM-Tg-rg-T27700-Ab-1/ GM-Tg-rg-T27700-Ab-2 | Anti-Rat CXCL13 monoclonal antibody | Rat |
| GM-Tg-mg-T27700-Ab-1/ GM-Tg-mg-T27700-Ab-2 | Anti-Mouse CXCL13 monoclonal antibody | Mouse |
| GM-Tg-cynog-T27700-Ab-1/ GM-Tg-cynog-T27700-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CXCL13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T27700-Ab-1/ GM-Tg-felg-T27700-Ab-2 | Anti-Feline CXCL13 monoclonal antibody | Feline |
| GM-Tg-cang-T27700-Ab-1/ GM-Tg-cang-T27700-Ab-2 | Anti-Canine CXCL13 monoclonal antibody | Canine |
| GM-Tg-bovg-T27700-Ab-1/ GM-Tg-bovg-T27700-Ab-2 | Anti-Bovine CXCL13 monoclonal antibody | Bovine |
| GM-Tg-equg-T27700-Ab-1/ GM-Tg-equg-T27700-Ab-2 | Anti-Equine CXCL13 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T27700-Ab-1/ GM-Tg-hg-T27700-Ab-2; GM-Tg-rg-T27700-Ab-1/ GM-Tg-rg-T27700-Ab-2; GM-Tg-mg-T27700-Ab-1/ GM-Tg-mg-T27700-Ab-2; GM-Tg-cynog-T27700-Ab-1/ GM-Tg-cynog-T27700-Ab-2; GM-Tg-felg-T27700-Ab-1/ GM-Tg-felg-T27700-Ab-2; GM-Tg-cang-T27700-Ab-1/ GM-Tg-cang-T27700-Ab-2; GM-Tg-bovg-T27700-Ab-1/ GM-Tg-bovg-T27700-Ab-2; GM-Tg-equg-T27700-Ab-1/ GM-Tg-equg-T27700-Ab-2 |
| Products Name | Anti-CXCL13 monoclonal antibody |
| Format | mab |
| Target Name | CXCL13 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CXCL13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T27700-Ag-1 | Recombinant multi-species CXL13/ CXCL13/ ANGIE protein |
| Cytokine | GM-Tg-g-T27700-Ag-1 | chemokine (C-X-C motif) ligand 13 (CXCL13) protein |
| ORF Viral Vector | pGMLP001932 | human CXCL13 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001932 | human CXCL13 Lentivirus particle |
| ORF Viral Vector | pGMLPm000069 | mouse Cxcl13 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000069 | mouse Cxcl13 Lentivirus particle |
Target information
| Target ID | GM-T27700 |
| Target Name | CXCL13 |
| Gene ID | 10563,55985,498335,574224,608156,101096888,511674,100629997 |
| Gene Symbol and Synonyms | 4631412M08Rik,ANGIE,ANGIE2,BCA-1,BCA1,BLC,BLR1L,CXCL13,SCYB13 |
| Uniprot Accession | O43927 |
| Uniprot Entry Name | CXL13_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000156234 |
| Target Classification | N/A |
The target: CXCL13, gene name: CXCL13, also named as ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13. B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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