Anti-FGF7/ HBGF-7/ KGF functional antibody

Anti-FGF7/ HBGF-7/ KGF functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to FGF7/FGF7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T19852-Ab-1/ GM-Tg-hg-T19852-Ab-2Anti-Human FGF7 monoclonal antibodyHuman
GM-Tg-rg-T19852-Ab-1/ GM-Tg-rg-T19852-Ab-2Anti-Rat FGF7 monoclonal antibodyRat
GM-Tg-mg-T19852-Ab-1/ GM-Tg-mg-T19852-Ab-2Anti-Mouse FGF7 monoclonal antibodyMouse
GM-Tg-cynog-T19852-Ab-1/ GM-Tg-cynog-T19852-Ab-2Anti-Cynomolgus/ Rhesus macaque FGF7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T19852-Ab-1/ GM-Tg-felg-T19852-Ab-2Anti-Feline FGF7 monoclonal antibodyFeline
GM-Tg-cang-T19852-Ab-1/ GM-Tg-cang-T19852-Ab-2Anti-Canine FGF7 monoclonal antibodyCanine
GM-Tg-bovg-T19852-Ab-1/ GM-Tg-bovg-T19852-Ab-2Anti-Bovine FGF7 monoclonal antibodyBovine
GM-Tg-equg-T19852-Ab-1/ GM-Tg-equg-T19852-Ab-2Anti-Equine FGF7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T19852-Ab-1/ GM-Tg-hg-T19852-Ab-2; GM-Tg-rg-T19852-Ab-1/ GM-Tg-rg-T19852-Ab-2;
GM-Tg-mg-T19852-Ab-1/ GM-Tg-mg-T19852-Ab-2; GM-Tg-cynog-T19852-Ab-1/ GM-Tg-cynog-T19852-Ab-2;
GM-Tg-felg-T19852-Ab-1/ GM-Tg-felg-T19852-Ab-2; GM-Tg-cang-T19852-Ab-1/ GM-Tg-cang-T19852-Ab-2;
GM-Tg-bovg-T19852-Ab-1/ GM-Tg-bovg-T19852-Ab-2; GM-Tg-equg-T19852-Ab-1/ GM-Tg-equg-T19852-Ab-2
Products NameAnti-FGF7 monoclonal antibody
Formatmab
Target NameFGF7
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FGF7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T19852-Ag-1Recombinant multi-species FGF7/ HBGF-7/ KGF protein
    CytokineGM-Tg-g-T19852-Ag-1fibroblast growth factor 7 (FGF7) protein
    ORF Viral VectorvGMLP004482human FGF7 Lentivirus particle
    ORF Viral VectorpGMLP004482human FGF7 Lentivirus plasmid
    ORF Viral VectorpGMLPm001037mouse Fgf7 Lentivirus plasmid
    ORF Viral VectorpGMLPm005408mouse Fgf7 Lentivirus plasmid
    ORF Viral VectorvGMLPm001037mouse Fgf7 Lentivirus particle
    ORF Viral VectorvGMLPm005408mouse Fgf7 Lentivirus particle


    Target information

    Target IDGM-T19852
    Target NameFGF7
    Gene ID2252,14178,29348,574345,403915,101097982,616885,100033961
    Gene Symbol and SynonymsFgf5b,FGF7,HBGF-7,KGF,KGF/FGF7
    Uniprot AccessionP21781,Q02195,P79150
    Uniprot Entry NameFGF7_HUMAN,FGF7_RAT,FGF7_CANLF
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target, Cytokine Target
    DiseaseAcute respiratory distress syndrome (ARDS)
    Gene EnsemblENSG00000140285
    Target ClassificationN/A

    The target: FGF7, gene name: FGF7, also named as HBGF-7, KGF. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.