Anti-RHCG/ C15orf6/ PDRC2 monoclonal antibody

Anti-RHCG/ C15orf6/ PDRC2 antibody for FACS & in-vivo assay

Target products collectionGo to RHCG/RHCG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T17291-Ab-1/ GM-Tg-hg-T17291-Ab-2Anti-Human RHCG monoclonal antibodyHuman
GM-Tg-rg-T17291-Ab-1/ GM-Tg-rg-T17291-Ab-2Anti-Rat RHCG monoclonal antibodyRat
GM-Tg-mg-T17291-Ab-1/ GM-Tg-mg-T17291-Ab-2Anti-Mouse RHCG monoclonal antibodyMouse
GM-Tg-cynog-T17291-Ab-1/ GM-Tg-cynog-T17291-Ab-2Anti-Cynomolgus/ Rhesus macaque RHCG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T17291-Ab-1/ GM-Tg-felg-T17291-Ab-2Anti-Feline RHCG monoclonal antibodyFeline
GM-Tg-cang-T17291-Ab-1/ GM-Tg-cang-T17291-Ab-2Anti-Canine RHCG monoclonal antibodyCanine
GM-Tg-bovg-T17291-Ab-1/ GM-Tg-bovg-T17291-Ab-2Anti-Bovine RHCG monoclonal antibodyBovine
GM-Tg-equg-T17291-Ab-1/ GM-Tg-equg-T17291-Ab-2Anti-Equine RHCG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T17291-Ab-1/ GM-Tg-hg-T17291-Ab-2; GM-Tg-rg-T17291-Ab-1/ GM-Tg-rg-T17291-Ab-2;
GM-Tg-mg-T17291-Ab-1/ GM-Tg-mg-T17291-Ab-2; GM-Tg-cynog-T17291-Ab-1/ GM-Tg-cynog-T17291-Ab-2;
GM-Tg-felg-T17291-Ab-1/ GM-Tg-felg-T17291-Ab-2; GM-Tg-cang-T17291-Ab-1/ GM-Tg-cang-T17291-Ab-2;
GM-Tg-bovg-T17291-Ab-1/ GM-Tg-bovg-T17291-Ab-2; GM-Tg-equg-T17291-Ab-1/ GM-Tg-equg-T17291-Ab-2
Products NameAnti-RHCG monoclonal antibody
Formatmab
Target NameRHCG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RHCG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RHCG/ C15orf6/ PDRC2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T17291
    Target NameRHCG
    Gene ID51458,56315,293048,664731,479040,101083517,281456,100069692
    Gene Symbol and SynonymsC15orf6,PDRC2,RHCG,RHGK,SLC42A3
    Uniprot AccessionQ9UBD6,Q7TNN9,Q20CR3,Q3BCQ4,Q2T9S6
    Uniprot Entry NameRHCG_HUMAN,RHCG_MACMU,RHCG_RAT,RHCG_CANLF,RHCG_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000140519
    Target ClassificationN/A

    The target: RHCG, gene name: RHCG, also named as C15orf6, PDRC2, RHGK, SLC42A3. Enables ammonium transmembrane transporter activity; ankyrin binding activity; and identical protein binding activity. Involved in ammonium transmembrane transport; cellular ion homeostasis; and transepithelial ammonium transport. Located in apical plasma membrane and basolateral plasma membrane. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.