Anti-SENP8 monoclonal antibody

Pre-made anti-SENP8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SENP8/SENP8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T13928-Ab-1/ GM-Tg-hg-T13928-Ab-2Anti-Human SENP8 monoclonal antibodyHuman
GM-Tg-rg-T13928-Ab-1/ GM-Tg-rg-T13928-Ab-2Anti-Rat SENP8 monoclonal antibodyRat
GM-Tg-mg-T13928-Ab-1/ GM-Tg-mg-T13928-Ab-2Anti-Mouse SENP8 monoclonal antibodyMouse
GM-Tg-cynog-T13928-Ab-1/ GM-Tg-cynog-T13928-Ab-2Anti-Cynomolgus/ Rhesus macaque SENP8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T13928-Ab-1/ GM-Tg-felg-T13928-Ab-2Anti-Feline SENP8 monoclonal antibodyFeline
GM-Tg-cang-T13928-Ab-1/ GM-Tg-cang-T13928-Ab-2Anti-Canine SENP8 monoclonal antibodyCanine
GM-Tg-bovg-T13928-Ab-1/ GM-Tg-bovg-T13928-Ab-2Anti-Bovine SENP8 monoclonal antibodyBovine
GM-Tg-equg-T13928-Ab-1/ GM-Tg-equg-T13928-Ab-2Anti-Equine SENP8 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T13928-Ab-1/ GM-Tg-hg-T13928-Ab-2; GM-Tg-rg-T13928-Ab-1/ GM-Tg-rg-T13928-Ab-2;
GM-Tg-mg-T13928-Ab-1/ GM-Tg-mg-T13928-Ab-2; GM-Tg-cynog-T13928-Ab-1/ GM-Tg-cynog-T13928-Ab-2;
GM-Tg-felg-T13928-Ab-1/ GM-Tg-felg-T13928-Ab-2; GM-Tg-cang-T13928-Ab-1/ GM-Tg-cang-T13928-Ab-2;
GM-Tg-bovg-T13928-Ab-1/ GM-Tg-bovg-T13928-Ab-2; GM-Tg-equg-T13928-Ab-1/ GM-Tg-equg-T13928-Ab-2
Products NameAnti-SENP8 monoclonal antibody
Formatmab
Target NameSENP8
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SENP8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T13928-Ag-1Recombinant multi-species SENP8/ DEN1/ NEDP1 protein


    Target information

    Target IDGM-T13928
    Target NameSENP8
    Gene ID123228,71599,315723,697613,487631,101096986,513300,100052291
    Gene Symbol and Synonyms9130010J17Rik,DEN1,NEDP1,PRSC2,SENP8
    Uniprot AccessionQ96LD8,Q5FVJ8
    Uniprot Entry NameSENP8_HUMAN,SENP8_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000166192
    Target ClassificationN/A

    The target: SENP8, gene name: SENP8, also named as DEN1, NEDP1, PRSC2. This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.