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Anti-CRY1 monoclonal antibody
Pre-made anti-CRY1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CRY1/CRY1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T12108-Ab-1/ GM-Tg-hg-T12108-Ab-2 | Anti-Human CRY1 monoclonal antibody | Human |
| GM-Tg-rg-T12108-Ab-1/ GM-Tg-rg-T12108-Ab-2 | Anti-Rat CRY1 monoclonal antibody | Rat |
| GM-Tg-mg-T12108-Ab-1/ GM-Tg-mg-T12108-Ab-2 | Anti-Mouse CRY1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T12108-Ab-1/ GM-Tg-cynog-T12108-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CRY1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T12108-Ab-1/ GM-Tg-felg-T12108-Ab-2 | Anti-Feline CRY1 monoclonal antibody | Feline |
| GM-Tg-cang-T12108-Ab-1/ GM-Tg-cang-T12108-Ab-2 | Anti-Canine CRY1 monoclonal antibody | Canine |
| GM-Tg-bovg-T12108-Ab-1/ GM-Tg-bovg-T12108-Ab-2 | Anti-Bovine CRY1 monoclonal antibody | Bovine |
| GM-Tg-equg-T12108-Ab-1/ GM-Tg-equg-T12108-Ab-2 | Anti-Equine CRY1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T12108-Ab-1/ GM-Tg-hg-T12108-Ab-2; GM-Tg-rg-T12108-Ab-1/ GM-Tg-rg-T12108-Ab-2; GM-Tg-mg-T12108-Ab-1/ GM-Tg-mg-T12108-Ab-2; GM-Tg-cynog-T12108-Ab-1/ GM-Tg-cynog-T12108-Ab-2; GM-Tg-felg-T12108-Ab-1/ GM-Tg-felg-T12108-Ab-2; GM-Tg-cang-T12108-Ab-1/ GM-Tg-cang-T12108-Ab-2; GM-Tg-bovg-T12108-Ab-1/ GM-Tg-bovg-T12108-Ab-2; GM-Tg-equg-T12108-Ab-1/ GM-Tg-equg-T12108-Ab-2 |
| Products Name | Anti-CRY1 monoclonal antibody |
| Format | mab |
| Target Name | CRY1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CRY1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T12108-Ag-1 | Recombinant multi-species CRY1/ DSPD/ PHLL1 protein |
| ORF Viral Vector | vGMLP002938 | human CRY1 Lentivirus particle |
| ORF Viral Vector | pGMLP002938 | human CRY1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000167 | mouse Cry1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000167 | mouse Cry1 Lentivirus particle |
Target information
| Target ID | GM-T12108 |
| Target Name | CRY1 |
| Gene ID | 1407,12952,299691,703752,474528,101089451,535947,100034165 |
| Gene Symbol and Synonyms | CRY1,DSPD,PHLL1 |
| Uniprot Accession | Q16526,Q32Q86 |
| Uniprot Entry Name | CRY1_HUMAN,CRY1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000008405 |
| Target Classification | N/A |
The target: CRY1, gene name: CRY1, also named as DSPD, PHLL1. This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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