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Anti-KMT5B monoclonal antibody
Pre-made anti-KMT5B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to KMT5B/KMT5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T05164-Ab-1/ GM-Tg-hg-T05164-Ab-2 | Anti-Human KMT5B monoclonal antibody | Human |
| GM-Tg-rg-T05164-Ab-1/ GM-Tg-rg-T05164-Ab-2 | Anti-Rat KMT5B monoclonal antibody | Rat |
| GM-Tg-mg-T05164-Ab-1/ GM-Tg-mg-T05164-Ab-2 | Anti-Mouse KMT5B monoclonal antibody | Mouse |
| GM-Tg-cynog-T05164-Ab-1/ GM-Tg-cynog-T05164-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KMT5B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T05164-Ab-1/ GM-Tg-felg-T05164-Ab-2 | Anti-Feline KMT5B monoclonal antibody | Feline |
| GM-Tg-cang-T05164-Ab-1/ GM-Tg-cang-T05164-Ab-2 | Anti-Canine KMT5B monoclonal antibody | Canine |
| GM-Tg-bovg-T05164-Ab-1/ GM-Tg-bovg-T05164-Ab-2 | Anti-Bovine KMT5B monoclonal antibody | Bovine |
| GM-Tg-equg-T05164-Ab-1/ GM-Tg-equg-T05164-Ab-2 | Anti-Equine KMT5B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T05164-Ab-1/ GM-Tg-hg-T05164-Ab-2; GM-Tg-rg-T05164-Ab-1/ GM-Tg-rg-T05164-Ab-2; GM-Tg-mg-T05164-Ab-1/ GM-Tg-mg-T05164-Ab-2; GM-Tg-cynog-T05164-Ab-1/ GM-Tg-cynog-T05164-Ab-2; GM-Tg-felg-T05164-Ab-1/ GM-Tg-felg-T05164-Ab-2; GM-Tg-cang-T05164-Ab-1/ GM-Tg-cang-T05164-Ab-2; GM-Tg-bovg-T05164-Ab-1/ GM-Tg-bovg-T05164-Ab-2; GM-Tg-equg-T05164-Ab-1/ GM-Tg-equg-T05164-Ab-2 |
| Products Name | Anti-KMT5B monoclonal antibody |
| Format | mab |
| Target Name | KMT5B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KMT5B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T05164-Ag-1 | Recombinant multi-species KMT5B/ CGI-85/ CGI85 protein |
| ORF Viral Vector | pGMLPm004751 | mouse Kmt5b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004751 | mouse Kmt5b Lentivirus particle |
Target information
| Target ID | GM-T05164 |
| Target Name | KMT5B |
| Gene ID | 51111,225888,361688,710481,483690,101094702,767828,100053438 |
| Gene Symbol and Synonyms | C630029K18Rik,CGI-85,CGI85,KMT5B,MRD51,Suv4-20h1,SUV420H1 |
| Uniprot Accession | Q4FZB7,P0C2N5,Q29RP8 |
| Uniprot Entry Name | KMT5B_HUMAN,KMT5B_RAT,KMT5B_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000110066 |
| Target Classification | N/A |
The target: KMT5B, gene name: KMT5B, also named as CGI-85, CGI85, MRD51, SUV420H1. This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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