Anti-NMUR2/ FM-4/ FM4 monoclonal antibody

Anti-NMUR2/ FM-4/ FM4 antibody for FACS & in-vivo assay

Target products collectionGo to NMUR2/NMUR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T04210-Ab-1/ GM-Tg-hg-T04210-Ab-2Anti-Human NMUR2 monoclonal antibodyHuman
GM-Tg-rg-T04210-Ab-1/ GM-Tg-rg-T04210-Ab-2Anti-Rat NMUR2 monoclonal antibodyRat
GM-Tg-mg-T04210-Ab-1/ GM-Tg-mg-T04210-Ab-2Anti-Mouse NMUR2 monoclonal antibodyMouse
GM-Tg-cynog-T04210-Ab-1/ GM-Tg-cynog-T04210-Ab-2Anti-Cynomolgus/ Rhesus macaque NMUR2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T04210-Ab-1/ GM-Tg-felg-T04210-Ab-2Anti-Feline NMUR2 monoclonal antibodyFeline
GM-Tg-cang-T04210-Ab-1/ GM-Tg-cang-T04210-Ab-2Anti-Canine NMUR2 monoclonal antibodyCanine
GM-Tg-bovg-T04210-Ab-1/ GM-Tg-bovg-T04210-Ab-2Anti-Bovine NMUR2 monoclonal antibodyBovine
GM-Tg-equg-T04210-Ab-1/ GM-Tg-equg-T04210-Ab-2Anti-Equine NMUR2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T04210-Ab-1/ GM-Tg-hg-T04210-Ab-2; GM-Tg-rg-T04210-Ab-1/ GM-Tg-rg-T04210-Ab-2;
GM-Tg-mg-T04210-Ab-1/ GM-Tg-mg-T04210-Ab-2; GM-Tg-cynog-T04210-Ab-1/ GM-Tg-cynog-T04210-Ab-2;
GM-Tg-felg-T04210-Ab-1/ GM-Tg-felg-T04210-Ab-2; GM-Tg-cang-T04210-Ab-1/ GM-Tg-cang-T04210-Ab-2;
GM-Tg-bovg-T04210-Ab-1/ GM-Tg-bovg-T04210-Ab-2; GM-Tg-equg-T04210-Ab-1/ GM-Tg-equg-T04210-Ab-2
Products NameAnti-NMUR2 monoclonal antibody
Formatmab
Target NameNMUR2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NMUR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NMUR2/ FM-4/ FM4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T04210
    Target NameNMUR2
    Gene ID56923,216749,64042,714051,489170,101083911,507439,100071477
    Gene Symbol and SynonymsFM-4,FM4,NMU-R2,NMU2R,NMUR2,TGR-1,TGR1
    Uniprot AccessionQ9GZQ4,Q9ESQ4,Q58CW4
    Uniprot Entry NameNMUR2_HUMAN,NMUR2_RAT,NMUR2_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000132911
    Target ClassificationN/A

    The target: NMUR2, gene name: NMUR2, also named as FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1. This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.