Anti-TGRM1/ TOGARAM1/ FAM179B functional antibody

Anti-TGRM1/ TOGARAM1/ FAM179B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TOGARAM1/TOGARAM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1650-Ab-1/ GM-Tg-hg-SE1650-Ab-2Anti-Human TOGARAM1 monoclonal antibodyHuman
GM-Tg-rg-SE1650-Ab-1/ GM-Tg-rg-SE1650-Ab-2Anti-Rat TOGARAM1 monoclonal antibodyRat
GM-Tg-mg-SE1650-Ab-1/ GM-Tg-mg-SE1650-Ab-2Anti-Mouse TOGARAM1 monoclonal antibodyMouse
GM-Tg-cynog-SE1650-Ab-1/ GM-Tg-cynog-SE1650-Ab-2Anti-Cynomolgus/ Rhesus macaque TOGARAM1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1650-Ab-1/ GM-Tg-felg-SE1650-Ab-2Anti-Feline TOGARAM1 monoclonal antibodyFeline
GM-Tg-cang-SE1650-Ab-1/ GM-Tg-cang-SE1650-Ab-2Anti-Canine TOGARAM1 monoclonal antibodyCanine
GM-Tg-bovg-SE1650-Ab-1/ GM-Tg-bovg-SE1650-Ab-2Anti-Bovine TOGARAM1 monoclonal antibodyBovine
GM-Tg-equg-SE1650-Ab-1/ GM-Tg-equg-SE1650-Ab-2Anti-Equine TOGARAM1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1650-Ab-1/ GM-Tg-hg-SE1650-Ab-2; GM-Tg-rg-SE1650-Ab-1/ GM-Tg-rg-SE1650-Ab-2;
GM-Tg-mg-SE1650-Ab-1/ GM-Tg-mg-SE1650-Ab-2; GM-Tg-cynog-SE1650-Ab-1/ GM-Tg-cynog-SE1650-Ab-2;
GM-Tg-felg-SE1650-Ab-1/ GM-Tg-felg-SE1650-Ab-2; GM-Tg-cang-SE1650-Ab-1/ GM-Tg-cang-SE1650-Ab-2;
GM-Tg-bovg-SE1650-Ab-1/ GM-Tg-bovg-SE1650-Ab-2; GM-Tg-equg-SE1650-Ab-1/ GM-Tg-equg-SE1650-Ab-2
Products NameAnti-TOGARAM1 monoclonal antibody
Formatmab
Target NameTOGARAM1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TOGARAM1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1650-Ag-1Recombinant multi-species TGRM1/ TOGARAM1/ FAM179B protein


    Target information

    Target IDGM-SE1650
    Target NameTOGARAM1
    Gene ID23116,328108,314169,702188,490669,101089018,540222,100051392
    Gene Symbol and SynonymsA430041B07Rik,C130034K06,FAM179B,JBTS37,KIAA0423,RGD1310474,TOGARAM1
    Uniprot AccessionQ9Y4F4
    Uniprot Entry NameTGRM1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198718
    Target ClassificationN/A

    The target: TOGARAM1, gene name: TOGARAM1, also named as FAM179B, KIAA0423. Predicted to enable microtubule binding activity. Predicted to be involved in organelle assembly and positive regulation of microtubule polymerization. Predicted to be located in ciliary basal body. Predicted to be active in cilium and microtubule cytoskeleton. Predicted to colocalize with microtubule. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.