Anti-MEX3C/ BM-013/ MEX-3C functional antibody

Anti-MEX3C/ BM-013/ MEX-3C functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MEX3C/MEX3C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1615-Ab-1/ GM-Tg-hg-SE1615-Ab-2Anti-Human MEX3C monoclonal antibodyHuman
GM-Tg-rg-SE1615-Ab-1/ GM-Tg-rg-SE1615-Ab-2Anti-Rat MEX3C monoclonal antibodyRat
GM-Tg-mg-SE1615-Ab-1/ GM-Tg-mg-SE1615-Ab-2Anti-Mouse MEX3C monoclonal antibodyMouse
GM-Tg-cynog-SE1615-Ab-1/ GM-Tg-cynog-SE1615-Ab-2Anti-Cynomolgus/ Rhesus macaque MEX3C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1615-Ab-1/ GM-Tg-felg-SE1615-Ab-2Anti-Feline MEX3C monoclonal antibodyFeline
GM-Tg-cang-SE1615-Ab-1/ GM-Tg-cang-SE1615-Ab-2Anti-Canine MEX3C monoclonal antibodyCanine
GM-Tg-bovg-SE1615-Ab-1/ GM-Tg-bovg-SE1615-Ab-2Anti-Bovine MEX3C monoclonal antibodyBovine
GM-Tg-equg-SE1615-Ab-1/ GM-Tg-equg-SE1615-Ab-2Anti-Equine MEX3C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1615-Ab-1/ GM-Tg-hg-SE1615-Ab-2; GM-Tg-rg-SE1615-Ab-1/ GM-Tg-rg-SE1615-Ab-2;
GM-Tg-mg-SE1615-Ab-1/ GM-Tg-mg-SE1615-Ab-2; GM-Tg-cynog-SE1615-Ab-1/ GM-Tg-cynog-SE1615-Ab-2;
GM-Tg-felg-SE1615-Ab-1/ GM-Tg-felg-SE1615-Ab-2; GM-Tg-cang-SE1615-Ab-1/ GM-Tg-cang-SE1615-Ab-2;
GM-Tg-bovg-SE1615-Ab-1/ GM-Tg-bovg-SE1615-Ab-2; GM-Tg-equg-SE1615-Ab-1/ GM-Tg-equg-SE1615-Ab-2
Products NameAnti-MEX3C monoclonal antibody
Formatmab
Target NameMEX3C
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MEX3C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1615-Ag-1Recombinant multi-species MEX3C/ BM-013/ MEX-3C protein


    Target information

    Target IDGM-SE1615
    Target NameMEX3C
    Gene ID51320,240396,307271,702158,476195,101095137,529318,100069803
    Gene Symbol and SynonymsA130001D14Rik,BM-013,MEX-3C,MEX3C,RKHD2,RNF194
    Uniprot AccessionQ5U5Q3
    Uniprot Entry NameMEX3C_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000176624
    Target ClassificationN/A

    The target: MEX3C, gene name: MEX3C, also named as BM-013, MEX-3C, RKHD2, RNF194. This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.