Anti-ZN449/ ZNF449/ ZSCAN19 functional antibody

Anti-ZN449/ ZNF449/ ZSCAN19 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ZNF449/ZNF449 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1604-Ab-1/ GM-Tg-hg-SE1604-Ab-2Anti-Human ZNF449 monoclonal antibodyHuman
GM-Tg-rg-SE1604-Ab-1/ GM-Tg-rg-SE1604-Ab-2Anti-Rat ZNF449 monoclonal antibodyRat
GM-Tg-mg-SE1604-Ab-1/ GM-Tg-mg-SE1604-Ab-2Anti-Mouse ZNF449 monoclonal antibodyMouse
GM-Tg-cynog-SE1604-Ab-1/ GM-Tg-cynog-SE1604-Ab-2Anti-Cynomolgus/ Rhesus macaque ZNF449 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1604-Ab-1/ GM-Tg-felg-SE1604-Ab-2Anti-Feline ZNF449 monoclonal antibodyFeline
GM-Tg-cang-SE1604-Ab-1/ GM-Tg-cang-SE1604-Ab-2Anti-Canine ZNF449 monoclonal antibodyCanine
GM-Tg-bovg-SE1604-Ab-1/ GM-Tg-bovg-SE1604-Ab-2Anti-Bovine ZNF449 monoclonal antibodyBovine
GM-Tg-equg-SE1604-Ab-1/ GM-Tg-equg-SE1604-Ab-2Anti-Equine ZNF449 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1604-Ab-1/ GM-Tg-hg-SE1604-Ab-2; GM-Tg-rg-SE1604-Ab-1/ GM-Tg-rg-SE1604-Ab-2;
GM-Tg-mg-SE1604-Ab-1/ GM-Tg-mg-SE1604-Ab-2; GM-Tg-cynog-SE1604-Ab-1/ GM-Tg-cynog-SE1604-Ab-2;
GM-Tg-felg-SE1604-Ab-1/ GM-Tg-felg-SE1604-Ab-2; GM-Tg-cang-SE1604-Ab-1/ GM-Tg-cang-SE1604-Ab-2;
GM-Tg-bovg-SE1604-Ab-1/ GM-Tg-bovg-SE1604-Ab-2; GM-Tg-equg-SE1604-Ab-1/ GM-Tg-equg-SE1604-Ab-2
Products NameAnti-ZNF449 monoclonal antibody
Formatmab
Target NameZNF449
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZNF449 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1604-Ag-1Recombinant multi-species ZN449/ ZNF449/ ZSCAN19 protein


    Target information

    Target IDGM-SE1604
    Target NameZNF449
    Gene ID203523,78619,684901,711148,119868522,111556244,512036,100057349
    Gene Symbol and Synonyms9530049C15Rik,Zfp449,ZNF449,ZSCAN19
    Uniprot AccessionQ6P9G9
    Uniprot Entry NameZN449_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000173275
    Target ClassificationN/A

    The target: ZNF449, gene name: ZNF449, also named as ZSCAN19. This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.