- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SCMC2/ SLC25A25/ MCSC functional antibody
Anti-SCMC2/ SLC25A25/ MCSC functional antibody for cell culture, ELISA & in-vivo assay
Go to SLC25A25/SLC25A25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1535-Ab-1/ GM-Tg-hg-SE1535-Ab-2 | Anti-Human SLC25A25 monoclonal antibody | Human |
| GM-Tg-rg-SE1535-Ab-1/ GM-Tg-rg-SE1535-Ab-2 | Anti-Rat SLC25A25 monoclonal antibody | Rat |
| GM-Tg-mg-SE1535-Ab-1/ GM-Tg-mg-SE1535-Ab-2 | Anti-Mouse SLC25A25 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1535-Ab-1/ GM-Tg-cynog-SE1535-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC25A25 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1535-Ab-1/ GM-Tg-felg-SE1535-Ab-2 | Anti-Feline SLC25A25 monoclonal antibody | Feline |
| GM-Tg-cang-SE1535-Ab-1/ GM-Tg-cang-SE1535-Ab-2 | Anti-Canine SLC25A25 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1535-Ab-1/ GM-Tg-bovg-SE1535-Ab-2 | Anti-Bovine SLC25A25 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1535-Ab-1/ GM-Tg-equg-SE1535-Ab-2 | Anti-Equine SLC25A25 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1535-Ab-1/ GM-Tg-hg-SE1535-Ab-2; GM-Tg-rg-SE1535-Ab-1/ GM-Tg-rg-SE1535-Ab-2; GM-Tg-mg-SE1535-Ab-1/ GM-Tg-mg-SE1535-Ab-2; GM-Tg-cynog-SE1535-Ab-1/ GM-Tg-cynog-SE1535-Ab-2; GM-Tg-felg-SE1535-Ab-1/ GM-Tg-felg-SE1535-Ab-2; GM-Tg-cang-SE1535-Ab-1/ GM-Tg-cang-SE1535-Ab-2; GM-Tg-bovg-SE1535-Ab-1/ GM-Tg-bovg-SE1535-Ab-2; GM-Tg-equg-SE1535-Ab-1/ GM-Tg-equg-SE1535-Ab-2 |
| Products Name | Anti-SLC25A25 monoclonal antibody |
| Format | mab |
| Target Name | SLC25A25 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC25A25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1535-Ag-1 | Recombinant multi-species SCMC2/ SLC25A25/ MCSC protein |
Target information
| Target ID | GM-SE1535 |
| Target Name | SLC25A25 |
| Gene ID | 114789,227731,246771,698216,491321,101095448,527786,100070341 |
| Gene Symbol and Synonyms | 1110030N17Rik,MCSC,mKIAA1896,PCSCL,SCAMC-2,SCAMC2,SLC25A25 |
| Uniprot Accession | Q6KCM7,Q8K3P6,Q0V7M4 |
| Uniprot Entry Name | SCMC2_HUMAN,SCMC2_RAT,SCMC2_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000148339 |
| Target Classification | N/A |
The target: SLC25A25, gene name: SLC25A25, also named as MCSC, PCSCL, SCAMC-2. The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
