Anti-SPAT6/ SPATA6/ HASH functional antibody

Anti-SPAT6/ SPATA6/ HASH functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SPATA6/SPATA6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1496-Ab-1/ GM-Tg-hg-SE1496-Ab-2Anti-Human SPATA6 monoclonal antibodyHuman
GM-Tg-rg-SE1496-Ab-1/ GM-Tg-rg-SE1496-Ab-2Anti-Rat SPATA6 monoclonal antibodyRat
GM-Tg-mg-SE1496-Ab-1/ GM-Tg-mg-SE1496-Ab-2Anti-Mouse SPATA6 monoclonal antibodyMouse
GM-Tg-cynog-SE1496-Ab-1/ GM-Tg-cynog-SE1496-Ab-2Anti-Cynomolgus/ Rhesus macaque SPATA6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1496-Ab-1/ GM-Tg-felg-SE1496-Ab-2Anti-Feline SPATA6 monoclonal antibodyFeline
GM-Tg-cang-SE1496-Ab-1/ GM-Tg-cang-SE1496-Ab-2Anti-Canine SPATA6 monoclonal antibodyCanine
GM-Tg-bovg-SE1496-Ab-1/ GM-Tg-bovg-SE1496-Ab-2Anti-Bovine SPATA6 monoclonal antibodyBovine
GM-Tg-equg-SE1496-Ab-1/ GM-Tg-equg-SE1496-Ab-2Anti-Equine SPATA6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1496-Ab-1/ GM-Tg-hg-SE1496-Ab-2; GM-Tg-rg-SE1496-Ab-1/ GM-Tg-rg-SE1496-Ab-2;
GM-Tg-mg-SE1496-Ab-1/ GM-Tg-mg-SE1496-Ab-2; GM-Tg-cynog-SE1496-Ab-1/ GM-Tg-cynog-SE1496-Ab-2;
GM-Tg-felg-SE1496-Ab-1/ GM-Tg-felg-SE1496-Ab-2; GM-Tg-cang-SE1496-Ab-1/ GM-Tg-cang-SE1496-Ab-2;
GM-Tg-bovg-SE1496-Ab-1/ GM-Tg-bovg-SE1496-Ab-2; GM-Tg-equg-SE1496-Ab-1/ GM-Tg-equg-SE1496-Ab-2
Products NameAnti-SPATA6 monoclonal antibody
Formatmab
Target NameSPATA6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SPATA6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1496-Ag-1Recombinant multi-species SPAT6/ SPATA6/ HASH protein


    Target information

    Target IDGM-SE1496
    Target NameSPATA6
    Gene ID54558,67946,171413,710827,475364,101098559,534169,100063364
    Gene Symbol and Synonyms1700062C23Rik,HASH,KRP,Mash,SPATA6,SRF-1,SRF1
    Uniprot AccessionQ9NWH7,Q99MU5,Q2KJG1
    Uniprot Entry NameSPAT6_HUMAN,SPAT6_RAT,SPAT6_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132122
    Target ClassificationN/A

    The target: SPATA6, gene name: SPATA6, also named as HASH, SRF-1, SRF1. Predicted to enable myosin light chain binding activity. Predicted to be involved in motile cilium assembly and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in sperm connecting piece. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.