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Anti-RT14/ MRPS14/ DJ262D12.2 functional antibody
Anti-RT14/ MRPS14/ DJ262D12.2 functional antibody for cell culture, ELISA & in-vivo assay
Go to MRPS14/MRPS14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1477-Ab-1/ GM-Tg-hg-SE1477-Ab-2 | Anti-Human MRPS14 monoclonal antibody | Human |
| GM-Tg-rg-SE1477-Ab-1/ GM-Tg-rg-SE1477-Ab-2 | Anti-Rat MRPS14 monoclonal antibody | Rat |
| GM-Tg-mg-SE1477-Ab-1/ GM-Tg-mg-SE1477-Ab-2 | Anti-Mouse MRPS14 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1477-Ab-1/ GM-Tg-cynog-SE1477-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MRPS14 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1477-Ab-1/ GM-Tg-felg-SE1477-Ab-2 | Anti-Feline MRPS14 monoclonal antibody | Feline |
| GM-Tg-cang-SE1477-Ab-1/ GM-Tg-cang-SE1477-Ab-2 | Anti-Canine MRPS14 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1477-Ab-1/ GM-Tg-bovg-SE1477-Ab-2 | Anti-Bovine MRPS14 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1477-Ab-1/ GM-Tg-equg-SE1477-Ab-2 | Anti-Equine MRPS14 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1477-Ab-1/ GM-Tg-hg-SE1477-Ab-2; GM-Tg-rg-SE1477-Ab-1/ GM-Tg-rg-SE1477-Ab-2; GM-Tg-mg-SE1477-Ab-1/ GM-Tg-mg-SE1477-Ab-2; GM-Tg-cynog-SE1477-Ab-1/ GM-Tg-cynog-SE1477-Ab-2; GM-Tg-felg-SE1477-Ab-1/ GM-Tg-felg-SE1477-Ab-2; GM-Tg-cang-SE1477-Ab-1/ GM-Tg-cang-SE1477-Ab-2; GM-Tg-bovg-SE1477-Ab-1/ GM-Tg-bovg-SE1477-Ab-2; GM-Tg-equg-SE1477-Ab-1/ GM-Tg-equg-SE1477-Ab-2 |
| Products Name | Anti-MRPS14 monoclonal antibody |
| Format | mab |
| Target Name | MRPS14 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MRPS14 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1477-Ag-1 | Recombinant multi-species RT14/ MRPS14/ DJ262D12.2 protein |
Target information
| Target ID | GM-SE1477 |
| Target Name | MRPS14 |
| Gene ID | 63931,64659,289143,708475,480061,101096128,445421,100052668 |
| Gene Symbol and Synonyms | 1810032L21Rik,COXPD38,DJ262D12.2,HSMRPS14,MRP-S14,MRPS14,Rpms14,S14mt |
| Uniprot Accession | O60783,Q6B860 |
| Uniprot Entry Name | RT14_HUMAN,RT14_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000120333 |
| Target Classification | N/A |
The target: MRPS14, gene name: MRPS14, also named as DJ262D12.2, HSMRPS14, MRP-S14, S14mt. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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