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Anti-AT5F1/ ATP5PB/ ATP5F1 functional antibody
Anti-AT5F1/ ATP5PB/ ATP5F1 functional antibody for cell culture, ELISA & in-vivo assay
Go to ATP5PB/ATP5PB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1468-Ab-1/ GM-Tg-hg-SE1468-Ab-2 | Anti-Human ATP5PB monoclonal antibody | Human |
| GM-Tg-rg-SE1468-Ab-1/ GM-Tg-rg-SE1468-Ab-2 | Anti-Rat ATP5PB monoclonal antibody | Rat |
| GM-Tg-mg-SE1468-Ab-1/ GM-Tg-mg-SE1468-Ab-2 | Anti-Mouse ATP5PB monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1468-Ab-1/ GM-Tg-cynog-SE1468-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ATP5PB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1468-Ab-1/ GM-Tg-felg-SE1468-Ab-2 | Anti-Feline ATP5PB monoclonal antibody | Feline |
| GM-Tg-cang-SE1468-Ab-1/ GM-Tg-cang-SE1468-Ab-2 | Anti-Canine ATP5PB monoclonal antibody | Canine |
| GM-Tg-bovg-SE1468-Ab-1/ GM-Tg-bovg-SE1468-Ab-2 | Anti-Bovine ATP5PB monoclonal antibody | Bovine |
| GM-Tg-equg-SE1468-Ab-1/ GM-Tg-equg-SE1468-Ab-2 | Anti-Equine ATP5PB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1468-Ab-1/ GM-Tg-hg-SE1468-Ab-2; GM-Tg-rg-SE1468-Ab-1/ GM-Tg-rg-SE1468-Ab-2; GM-Tg-mg-SE1468-Ab-1/ GM-Tg-mg-SE1468-Ab-2; GM-Tg-cynog-SE1468-Ab-1/ GM-Tg-cynog-SE1468-Ab-2; GM-Tg-felg-SE1468-Ab-1/ GM-Tg-felg-SE1468-Ab-2; GM-Tg-cang-SE1468-Ab-1/ GM-Tg-cang-SE1468-Ab-2; GM-Tg-bovg-SE1468-Ab-1/ GM-Tg-bovg-SE1468-Ab-2; GM-Tg-equg-SE1468-Ab-1/ GM-Tg-equg-SE1468-Ab-2 |
| Products Name | Anti-ATP5PB monoclonal antibody |
| Format | mab |
| Target Name | ATP5PB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ATP5PB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1468-Ag-1 | Recombinant multi-species AT5F1/ ATP5PB/ ATP5F1 protein |
Target information
| Target ID | GM-SE1468 |
| Target Name | ATP5PB |
| Gene ID | 515,11950,171375,704072,101097006,282701,100058893 |
| Gene Symbol and Synonyms | ATP5F1,ATP5PB,PIG47 |
| Uniprot Accession | P24539,P19511,P13619 |
| Uniprot Entry Name | AT5F1_HUMAN,AT5F1_RAT,AT5F1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000116459 |
| Target Classification | N/A |
The target: ATP5PB, gene name: ATP5PB, also named as ATP5F1, PIG47. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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