Anti-PPA5/ ACP5/ HPAP functional antibody

Anti-PPA5/ ACP5/ HPAP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ACP5/ACP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1442-Ab-1/ GM-Tg-hg-SE1442-Ab-2Anti-Human ACP5 monoclonal antibodyHuman
GM-Tg-rg-SE1442-Ab-1/ GM-Tg-rg-SE1442-Ab-2Anti-Rat ACP5 monoclonal antibodyRat
GM-Tg-mg-SE1442-Ab-1/ GM-Tg-mg-SE1442-Ab-2Anti-Mouse ACP5 monoclonal antibodyMouse
GM-Tg-cynog-SE1442-Ab-1/ GM-Tg-cynog-SE1442-Ab-2Anti-Cynomolgus/ Rhesus macaque ACP5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1442-Ab-1/ GM-Tg-felg-SE1442-Ab-2Anti-Feline ACP5 monoclonal antibodyFeline
GM-Tg-cang-SE1442-Ab-1/ GM-Tg-cang-SE1442-Ab-2Anti-Canine ACP5 monoclonal antibodyCanine
GM-Tg-bovg-SE1442-Ab-1/ GM-Tg-bovg-SE1442-Ab-2Anti-Bovine ACP5 monoclonal antibodyBovine
GM-Tg-equg-SE1442-Ab-1/ GM-Tg-equg-SE1442-Ab-2Anti-Equine ACP5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1442-Ab-1/ GM-Tg-hg-SE1442-Ab-2; GM-Tg-rg-SE1442-Ab-1/ GM-Tg-rg-SE1442-Ab-2;
GM-Tg-mg-SE1442-Ab-1/ GM-Tg-mg-SE1442-Ab-2; GM-Tg-cynog-SE1442-Ab-1/ GM-Tg-cynog-SE1442-Ab-2;
GM-Tg-felg-SE1442-Ab-1/ GM-Tg-felg-SE1442-Ab-2; GM-Tg-cang-SE1442-Ab-1/ GM-Tg-cang-SE1442-Ab-2;
GM-Tg-bovg-SE1442-Ab-1/ GM-Tg-bovg-SE1442-Ab-2; GM-Tg-equg-SE1442-Ab-1/ GM-Tg-equg-SE1442-Ab-2
Products NameAnti-ACP5 monoclonal antibody
Formatmab
Target NameACP5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ACP5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1442-Ag-1Recombinant multi-species PPA5/ ACP5/ HPAP protein
    ORF Viral VectorpGMLP004133human ACP5 Lentivirus plasmid
    ORF Viral VectorvGMLP004133human ACP5 Lentivirus particle
    ORF Viral VectorpGMLPm003226mouse Acp5 Lentivirus plasmid
    ORF Viral VectorvGMLPm003226mouse Acp5 Lentivirus particle


    Target information

    Target IDGM-SE1442
    Target NameACP5
    Gene ID54,11433,25732,715071,476705,101100541,517002,100056621
    Gene Symbol and SynonymsACP5,HPAP,TRAcP,TRACP5a,TRACP5b,TRAP,TrATPase,TTRRAP
    Uniprot AccessionP13686,P29288
    Uniprot Entry NamePPA5_HUMAN,PPA5_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000102575
    Target ClassificationN/A

    The target: ACP5, gene name: ACP5, also named as HPAP, TRACP5a, TRACP5b, TRAP, TrATPase. This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.