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Anti-DHX29/ DDX29 functional antibody
Anti-DHX29/ DDX29 functional antibody for cell culture, ELISA & in-vivo assay
Go to DHX29/DHX29 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1413-Ab-1/ GM-Tg-hg-SE1413-Ab-2 | Anti-Human DHX29 monoclonal antibody | Human |
| GM-Tg-rg-SE1413-Ab-1/ GM-Tg-rg-SE1413-Ab-2 | Anti-Rat DHX29 monoclonal antibody | Rat |
| GM-Tg-mg-SE1413-Ab-1/ GM-Tg-mg-SE1413-Ab-2 | Anti-Mouse DHX29 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1413-Ab-1/ GM-Tg-cynog-SE1413-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DHX29 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1413-Ab-1/ GM-Tg-felg-SE1413-Ab-2 | Anti-Feline DHX29 monoclonal antibody | Feline |
| GM-Tg-cang-SE1413-Ab-1/ GM-Tg-cang-SE1413-Ab-2 | Anti-Canine DHX29 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1413-Ab-1/ GM-Tg-bovg-SE1413-Ab-2 | Anti-Bovine DHX29 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1413-Ab-1/ GM-Tg-equg-SE1413-Ab-2 | Anti-Equine DHX29 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1413-Ab-1/ GM-Tg-hg-SE1413-Ab-2; GM-Tg-rg-SE1413-Ab-1/ GM-Tg-rg-SE1413-Ab-2; GM-Tg-mg-SE1413-Ab-1/ GM-Tg-mg-SE1413-Ab-2; GM-Tg-cynog-SE1413-Ab-1/ GM-Tg-cynog-SE1413-Ab-2; GM-Tg-felg-SE1413-Ab-1/ GM-Tg-felg-SE1413-Ab-2; GM-Tg-cang-SE1413-Ab-1/ GM-Tg-cang-SE1413-Ab-2; GM-Tg-bovg-SE1413-Ab-1/ GM-Tg-bovg-SE1413-Ab-2; GM-Tg-equg-SE1413-Ab-1/ GM-Tg-equg-SE1413-Ab-2 |
| Products Name | Anti-DHX29 monoclonal antibody |
| Format | mab |
| Target Name | DHX29 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DHX29 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1413-Ag-1 | Recombinant multi-species DHX29/ DDX29 protein |
Target information
| Target ID | GM-SE1413 |
| Target Name | DHX29 |
| Gene ID | 54505,218629,100362324,706306,478060,101088051,512470,100052007 |
| Gene Symbol and Synonyms | 3732415M03,DDX29,Ddxx,DHX29,E130202M19Rik |
| Uniprot Accession | Q7Z478 |
| Uniprot Entry Name | DHX29_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000067248 |
| Target Classification | N/A |
The target: DHX29, gene name: DHX29, also named as DDX29. This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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